Literature DB >> 24240795

IgG4-related ocular adnexal disease mimicking thyroid-associated orbitopathy.

Hidefumi Inaba1, Takahiro Hayakawa, Waka Miyamoto, Ken Takeshima, Hiroyuki Yamaoka, Yasushi Furukawa, Hiromichi Kawashima, Hiroyuki Ariyasu, Hisao Wakasaki, Hiroto Furuta, Masahiro Nishi, Taisei Nakao, Hideyuki Sasaki, Yuka Okada, Kazuto Matsunaga, Yasushi Nakamura, Takashi Akamizu.   

Abstract

A 72-year-old man presented with bilateral eyelid swelling and redness. An orbital CT scan showed bilateral proptosis, extraocular muscle enlargement and swollen lacrimal glands, mimicking thyroid-associated orbitopathy (TAO) with Hashimoto's thyroiditis (HT). During the patient's clinical course, spontaneous remission of lung consolidation (35 × 26 mm) was seen. A diagnosis of IgG4-related disease (IgG4-RD) was made based on an elevated serum IgG4 level (1,020 mg/dL; normal, 4-108), predominance of IgG4-positive plasma cells (IgG4/IgG: 35/70 in HPF) in the lacrimal glands and typical features of Mikulicz's disease. This report provides a novel description of this unusual disease entity among HT, TAO and IgG4-RD.

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Year:  2013        PMID: 24240795     DOI: 10.2169/internalmedicine.52.0902

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  6 in total

1.  Serum immunoglobulin G4 levels and Graves' disease phenotype.

Authors:  Carmen Sorina Martin; Anca Elena Sirbu; Minodora Andreea Betivoiu; Suzana Florea; Carmen Gabriela Barbu; Simona Vasilica Fica
Journal:  Endocrine       Date:  2016-11-07       Impact factor: 3.633

2.  The Case of IgG4-related Ophthalmic Disease Accompanied by Compressive Optic Neuropathy.

Authors:  Marie Takeishi; Toshiyuki Oshitari; Satomi Ota; Takayuki Baba; Shuichi Yamamoto
Journal:  Neuroophthalmology       Date:  2017-10-25

Review 3.  Extraocular muscle enlargement.

Authors:  Khizar Rana; Valerie Juniat; Sandy Patel; Dinesh Selva
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2022-06-17       Impact factor: 3.535

Review 4.  Orbital inflammatory disease: Pictorial review and differential diagnosis.

Authors:  Michael N Pakdaman; Ali R Sepahdari; Sahar M Elkhamary
Journal:  World J Radiol       Date:  2014-04-28

Review 5.  Immunoglobulin G4-related diseases in the head and neck: a systematic review.

Authors:  Graeme B Mulholland; Caroline C Jeffery; Paras Satija; David W J Côté
Journal:  J Otolaryngol Head Neck Surg       Date:  2015-06-20

6.  A Case of Orbital Myositis Presenting With Dizziness.

Authors:  Neville Aquilina; Vincent Bugeja; Charmaine Zahra
Journal:  Open Access Maced J Med Sci       Date:  2018-07-13
  6 in total

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