| Literature DB >> 24239041 |
Monika Bekiesinska-Figatowska1, Orest Szczygielski2, Maria Boczar2, Jaroslaw Madzik3, Teresa Klepacka4, Elzbieta Michalak4, Anna Romaniuk-Doroszewska3, Maria Uliasz3, Pawel Peczkowski3, Ewa Sawicka2.
Abstract
Twenty-four children with giant congenital melanocytic nevi underwent brain MRI at 1.5 T scanner. Melanin deposits in the brain were found in seven children (29.2%) located in temporal lobes, thalamus, cerebellum, and pons. One patient showed leptomeningeal involvement. Six patients were asymptomatic, and one had epilepsy. As opposed to previous reports, localization of skin nevi on anterior part of trunk was correlated to central nervous system involvement. In all patients with brain involvement skin nevi showed picture of compound nevus with neurofibromatic component.Entities:
Keywords: Central nervous system (CNS); Giant congenital melanocytic nevi (GCMN); Magnetic resonance imaging (MRI); Neurocutaneous melanosis (NCM); Pathology
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Year: 2013 PMID： 24239041 DOI： 10.1016/j.clinimag.2013.10.001
Source DB: PubMed Journal: Clin Imaging ISSN： 0899-7071 Impact factor: 1.605