Literature DB >> 24238334

IRF4 provides rations for cytotoxic CD8(+) T cell soldiers.

Magdalena Huber1, Michael Lohoff.   

Abstract

The transcription factor IRF4 is known to be essential for differentiation of effector CD4(+) T cell subsets. In this issue, Yao et al. (2013) identify IRF4 as a regulator of checkpoints in the final steps and maintenance of CD8(+) T cell effector differentiation.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 24238334     DOI: 10.1016/j.immuni.2013.10.008

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  1 in total

1.  Cutting Edge: The Orphan Nuclear Receptor Nr4a1 Regulates CD8+ T Cell Expansion and Effector Function through Direct Repression of Irf4.

Authors:  Heba N Nowyhed; Tridu R Huynh; Graham D Thomas; Amy Blatchley; Catherine C Hedrick
Journal:  J Immunol       Date:  2015-09-11       Impact factor: 5.422

  1 in total

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