| Literature DB >> 24238228 |
Shu Hisata1, Hiroshi Moriyama, Ryushi Tazawa, Shinya Ohkouchi, Masakazu Ichinose, Masahito Ebina.
Abstract
We report a unique case of pulmonary alveolar proteinosis that developed 3 weeks after the Great East Japan Earthquake and the subsequent tsunami. The patient had inhaled dust repeatedly while visiting her devastated neighborhood without wearing a protective mask. Five weeks after the earthquake, lung samples taken from the patient showed foreign particle deposition; however, her serum was negative for GM-CSF autoantibody. The patient's clinical symptoms resolved following whole lung lavage. We conclude that inhalation of fine dust particles after natural disasters may cause the onset of pulmonary alveolar proteinosis.Entities:
Keywords: BALF; CEA; COPD; CT; Earthquake; GM-CSF; GM-CSF autoantibody; HRCT; KL-6; Krebs von den Lungen-6; PAP; Pulmonary alveolar proteinosis; SP-D; TBLB; Whole lung lavage; bronchoalveolar lavage fluid; carcinobembryonic antigen; chronic obstructive pulmonary disease; computed tomography; granulocyte macrophage colony-stimulating factor; high-resolution computed tomography; pulmonary alveolar proteinosis; surfactant protein D; transbronchial lung biopsy
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Year: 2013 PMID： 24238228 DOI： 10.1016/j.resinv.2013.04.005
Source DB: PubMed Journal: Respir Investig ISSN： 2212-5345