| Literature DB >> 24237985 |
Abstract
This review describes the epidemiology, pathophysiology, presentation, clinical causes, treatment, and long-term prognosis of pediatric patients who present with thrombotic microangiopathy. The focus is on hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, the most common phenotypes of thrombotic microangiopathy.Entities:
Keywords: Alternative pathway of complement (APC); Hemolytic uremic syndrome (HUS); Shiga toxin (Stx); Thrombotic microangiopathy (TMA); Thrombotic thrombocytopenic purpura (TTP)
Mesh:
Year: 2013 PMID: 24237985 PMCID: PMC3972058 DOI: 10.1016/j.pcl.2013.08.007
Source DB: PubMed Journal: Pediatr Clin North Am ISSN: 0031-3955 Impact factor: 3.278