| Literature DB >> 24237977 |
Alissa Martin1, Alexis A Thompson.
Abstract
The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.Entities:
Keywords: Anemia; Hemoglobinopathies; Iron overload; Thalassemia
Mesh:
Year: 2013 PMID: 24237977 DOI: 10.1016/j.pcl.2013.08.008
Source DB: PubMed Journal: Pediatr Clin North Am ISSN: 0031-3955 Impact factor: 3.278