Literature DB >> 24236543

Bladder cancer stem cells: biological and therapeutic perspectives.

G Goodwin Jinesh, Daniel Levi Willis, Ashish M Kamat1.   

Abstract

Bladder cancer stem cell research is rapidly expanding based on the knowledge of cancer stem cells from various cancer types and normal stem cells as models. In various cancer types, cancer stem cells have been implicated in therapeutic resistance and relapse after initial therapy. Understanding how cancer stem cells differ from bulk cancer cells and how cancer stem cells contribute to relapse and resistance are essential to develop novel therapeutics to target cancer stem cells effectively. Here we review the latest information on bladder cancer stem cells, their biological characteristics, including their response to treatment, recurrence, immune context and technical problems encountered in bladder cancer stem cell research.

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Year:  2014        PMID： 24236543     DOI： 10.2174/1574888x08666131113123051

Source DB:  PubMed          Journal:  Curr Stem Cell Res Ther        ISSN： 1574-888X            Impact factor:   3.828


  18 in total

Review 1.  Therapies targeting cancer stem cells: Current trends and future challenges.

Authors:  Denisa L Dragu; Laura G Necula; Coralia Bleotu; Carmen C Diaconu; Mihaela Chivu-Economescu
Journal:  World J Stem Cells       Date:  2015-10-26       Impact factor: 5.326

2.  Blebbishield emergency program: an apoptotic route to cellular transformation.

Authors:  G G Jinesh; A M Kamat
Journal:  Cell Death Differ       Date:  2016-03-11       Impact factor: 15.828

3.  β-Arrestins Regulate Stem Cell-Like Phenotype and Response to Chemotherapy in Bladder Cancer.

Authors:  Georgios Kallifatidis; Diandra K Smith; Daley S Morera; Jie Gao; Martin J Hennig; James J Hoy; Richard F Pearce; Isha R Dabke; Jiemin Li; Axel S Merseburger; Markus A Kuczyk; Vinata B Lokeshwar; Bal L Lokeshwar
Journal:  Mol Cancer Ther       Date:  2019-02-20       Impact factor: 6.261

4.  miR-126 promotes the growth and proliferation of leukemia stem cells by targeting DNA methyltransferase 1.

Authors:  Qian Ding; Qing Wang; Yi Ren; Hongqian Zhu; Zhujun Huang
Journal:  Int J Clin Exp Pathol       Date:  2018-07-01

5.  Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis.

Authors:  G G Jinesh; J R Molina; L Huang; N M Laing; G B Mills; M Bar-Eli; A M Kamat
Journal:  Cell Death Discov       Date:  2016-02-01

Review 6.  Bladder Cancer Stem-Like Cells: Their Origin and Therapeutic Perspectives.

Authors:  Tomokazu Ohishi; Fumitaka Koga; Toshiro Migita
Journal:  Int J Mol Sci       Date:  2015-12-29       Impact factor: 5.923

7.  RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program.

Authors:  Goodwin G Jinesh; Ashish M Kamat
Journal:  Cell Death Discov       Date:  2017-05-29

8.  Novel PKC-ζ to p47 phox interaction is necessary for transformation from blebbishields.

Authors:  Goodwin G Jinesh; Rikiya Taoka; Qiang Zhang; Siddharth Gorantla; Ashish M Kamat
Journal:  Sci Rep       Date:  2016-04-04       Impact factor: 4.379

9.  Endocytosis and serpentine filopodia drive blebbishield-mediated resurrection of apoptotic cancer stem cells.

Authors:  Goodwin G Jinesh; Ashish M Kamat
Journal:  Cell Death Discov       Date:  2016-01-25

10.  Surface PD-L1, E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis.

Authors:  Goodwin G Jinesh; Ganiraju C Manyam; Chinedu O Mmeje; Keith A Baggerly; Ashish M Kamat
Journal:  Sci Rep       Date:  2017-08-29       Impact factor: 4.379
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