| Literature DB >> 24236505 |
Pradeep Kumar1, Vishwajeet Jha, Rajesh Gonnade.
Abstract
A general organocatalytic strategy for asymmetric synthesis of both syn/anti-1,3-diamines has been developed. The strategy employs proline-catalyzed sequential α-amination and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes as the key step where syn-1,3-diamine was obtained as the most favorable product.Entities:
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Year: 2013 PMID： 24236505 DOI： 10.1021/jo401722e
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354