Literature DB >> 24235

Prostaglandin synthesis in human placenta and fetal membranes.

M J Duchesne, H Thaler-Dao, A C de Paulet.   

Abstract

The conversion of exogenous arachidonic acid into prostaglandins was studied in human placenta and fetal membrane microsomes. Only one prostaglandin was formed, prostaglandin E2 (PGE2), in fetal membrane microsomes. In placental microsomes PGE2 was further transformed into 15 keto-PGE2. Cofactor requirements and some characteristics of the system were studied. 1 to 3% conversion of arachidonic acid into prostaglandins was observed in placental microsomes and 5 to 8% conversion in fetal membrane microsomes.

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Year:  1978        PMID： 24235     DOI： 10.1016/s0090-6980(78)80003-3

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  11 in total

1.  The regulation of prostaglandin output from term intact fetal membranes by anti-inflammatory cytokines.

Authors:  N L Brown; S A Alvi; M G Elder; P R Bennett; M H Sullivan
Journal:  Immunology       Date:  2000-01       Impact factor: 7.397

2.  Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth.

Authors:  Haruta Mogami; Patrick W Keller; Haolin Shi; R Ann Word
Journal:  J Biol Chem       Date:  2014-03-20       Impact factor: 5.157

3.  Induction of Galphas contributes to the paradoxical stimulation of cytosolic phospholipase A2alpha expression by cortisol in human amnion fibroblasts.

Authors:  Chunming Guo; Jianneng Li; Leslie Myatt; Xiaoou Zhu; Kang Sun
Journal:  Mol Endocrinol       Date:  2010-03-04

4.  Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target.

Authors:  P J Jakobsson; S Thorén; R Morgenstern; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-22       Impact factor: 11.205

5.  Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition.

Authors:  Wang-Sheng Wang; Yi-Kai Lin; Fan Zhang; Wen-Jia Lei; Fang Pan; Ya-Nan Zhu; Jiang-Wen Lu; Chu-Yue Zhang; Qiong Zhou; Hao Ying; Kang Sun
Journal:  Cell Biosci       Date:  2022-05-18       Impact factor: 9.584

6.  Partial purification and characterization of a peroxidase activity from human placenta.

Authors:  J L Nelson; A P Kulkarni
Journal:  Biochem J       Date:  1990-06-15       Impact factor: 3.857

7.  Paradoxical stimulation of cyclooxygenase-2 expression by glucocorticoids via a cyclic AMP response element in human amnion fibroblasts.

Authors:  X O Zhu; Z Yang; C M Guo; X T Ni; J N Li; Y C Ge; L Myatt; K Sun
Journal:  Mol Endocrinol       Date:  2009-10-01

8.  Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.

Authors:  Haruta Mogami; Annavarapu Hari Kishore; Haolin Shi; Patrick W Keller; Yucel Akgul; R Ann Word
Journal:  J Biol Chem       Date:  2012-11-26       Impact factor: 5.157

9.  Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses.

Authors:  Yao Ye; Aurelia Vattai; Nina Ditsch; Christina Kuhn; Martina Rahmeh; Sven Mahner; Myriam Ripphahn; Roland Immler; Markus Sperandio; Udo Jeschke; Viktoria von Schönfeldt
Journal:  Endocr Connect       Date:  2018-04-26       Impact factor: 3.335

Review 10.  Serum amyloid A, a host-derived DAMP in pregnancy?

Authors:  Yi-Kai Lin; Ping Zhu; Wang-Sheng Wang; Kang Sun
Journal:  Front Immunol       Date:  2022-08-05       Impact factor: 8.786
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