Fate and exposure models in relation to risk assessment : Developments and validation criteria.

The recognition of potential long-term effects of substances, has led to the development of regulations and legislation which emphasis the need for assessing the risks posed by both new and existing substances for man and the environment. The evaluation of fate and exposure models is put into perspective in relation to the developments over the last five years in the framework of the EU regulations and national legislation within the European Community. The validation of environmental exposure models (multi-media models) is described in the context of quality assurance of models available to a user group, which is different from the quality assurance aspects for a developers group.