Literature DB >> 24234364

Use of enzymes in peptide synthesis.

I M Chaiken1, A Komoriya, M Ohno, F Widmer.   

Abstract

Recent experiments in several laboratories have emphasized the benefits of proteolytic enzymes as effective catalysts for the formation of peptide bonds for synthesis and semisynthesis. This review summarizes successful applications in both stepwise synthesis for small peptides and fragment condensation to produce large polypeptides and proteins.

Year:  1982        PMID: 24234364     DOI: 10.1007/BF02798320

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN: 0273-2289            Impact factor:   2.926


  37 in total

1.  From synthetic antigens to synthetic vaccines.

Authors:  M Sela
Journal:  Immunol Today       Date:  1981-08

2.  Letter: Carbonylbis(L-methionine p-nitrophenyl ester). A new reagent for the reversible intramolecular cross-linking of insulin.

Authors:  W D Busse; F H Carpenter
Journal:  J Am Chem Soc       Date:  1974-09-04       Impact factor: 15.419

3.  Co-oligopeptides of aromatic amino acids and glycine with variable distance between the aromatic residues. VII. Enzymatic synthesis of N-protected peptide amides.

Authors:  R Saltman; D Vlach; P L Luisi
Journal:  Biopolymers       Date:  1977-03       Impact factor: 2.505

4.  Enzymatic condensation of nonassociated peptide fragments using a molecular trap.

Authors:  G A Homandberg; A Komoriya; I M Chaiken
Journal:  Biochemistry       Date:  1982-07-06       Impact factor: 3.162

Review 5.  Proteinase-catalyzed synthesis of peptide bonds.

Authors:  J S Fruton
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1982

Review 6.  Effect of the microenvironment on the mode of action of immobilized enzymes.

Authors:  E Katchalski; I Silman; R Goldman
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1971

7.  Studies on protein semisynthesis. I. Formation of esters, hydrazides, and substituted hydrazides of peptides by the reverse reaction of trypsin.

Authors:  S Yagisawa
Journal:  J Biochem       Date:  1981-02       Impact factor: 3.387

8.  Human somatotropin: covalent reconstitution of two polypeptide contiguous fragments with thrombin.

Authors:  L Gráf; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205

9.  Intramolecular enzymatic peptide synthesis: trypsin-mediated coupling of the peptide bond between B22-arginine and B23-glycine in a split crosslinked insulin.

Authors:  S C Chu; C C Wang; D Brandenburg
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1981-06

10.  Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin.

Authors:  H Tager; N Thomas; R Assoian; A Rubenstein; M Saekow; J Olefsky; E T Kaiser
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

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  2 in total

1.  Enzymatic peptide synthesis by the recombinant proline-specific endopeptidase from Flavobacterium meningosepticum and its mutationally altered Cys-556 variant.

Authors:  F Krieg; N Wolf
Journal:  Appl Microbiol Biotechnol       Date:  1995-03       Impact factor: 4.813

Review 2.  Small and Random Peptides: An Unexplored Reservoir of Potentially Functional Primitive Organocatalysts. The Case of Seryl-Histidine.

Authors:  Rafal Wieczorek; Katarzyna Adamala; Tecla Gasperi; Fabio Polticelli; Pasquale Stano
Journal:  Life (Basel)       Date:  2017-04-09
  2 in total

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