Literature DB >> 24233786

Construction and application of site-specific artificial nucleases for targeted gene editing.

Fatma O Kok1, Ankit Gupta, Nathan D Lawson, Scot A Wolfe.   

Abstract

Artificial nucleases have developed into powerful tools for introducing precise genome modifications in a wide variety of species. In this chapter the authors provide detailed protocols for rapidly constructing zinc finger nucleases (ZFNs) and TALE nucleases (TALENs) and evaluating their activity for the targeted generation of InDels within the zebrafish genome.

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Year:  2014        PMID： 24233786     DOI： 10.1007/978-1-62703-721-1_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

1.  Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.

Authors:  F O Kok; M Shin; C-W Ni; A Gupta; A S Grosse; A van Impel; B C Kirchmaier; J Peterson-Maduro; G Kourkoulis; I Male; D F DeSantis; S Sheppard-Tindell; L Ebarasi; C Betsholtz; S Schulte-Merker; S A Wolfe; N D Lawson
Journal:  Dev Cell       Date:  2014-12-18       Impact factor: 12.270

2.  Vegfc acts through ERK to induce sprouting and differentiation of trunk lymphatic progenitors.

Authors:  Masahiro Shin; Ira Male; Timothy J Beane; Jacques A Villefranc; Fatma O Kok; Lihua J Zhu; Nathan D Lawson
Journal:  Development       Date:  2016-09-12       Impact factor: 6.868

3.  Targeted germ line disruptions reveal general and species-specific roles for paralog group 1 hox genes in zebrafish.

Authors:  Steven E Weicksel; Ankit Gupta; Denise A Zannino; Scot A Wolfe; Charles G Sagerström
Journal:  BMC Dev Biol       Date:  2014-06-05       Impact factor: 1.978

4.  DNA-binding-domain fusions enhance the targeting range and precision of Cas9.

Authors:  Mehmet Fatih Bolukbasi; Ankit Gupta; Sarah Oikemus; Alan G Derr; Manuel Garber; Michael H Brodsky; Lihua Julie Zhu; Scot A Wolfe
Journal:  Nat Methods       Date:  2015-10-19       Impact factor: 28.547

5.  FishNET: An automated relational database for zebrafish colony management.

Authors:  Abiud Cantu Gutierrez; Manuel Cantu Gutierrez; Alexander M Rhyner; Oscar E Ruiz; George T Eisenhoffer; Joshua D Wythe
Journal:  PLoS Biol       Date:  2019-06-20       Impact factor: 8.029

Review 6.  Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics.

Authors:  Tugba G Kucukkal; Ye Yang; Susan C Chapman; Weiguo Cao; Emil Alexov
Journal:  Int J Mol Sci       Date:  2014-05-30       Impact factor: 5.923
  6 in total

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