Literature DB >> 24233606

Fluorescence labeling and interaction of atherogenic lipoproteins with cultured cells.

G Hofer1, R Gorges, G M Kostner, F Paltauf, A Hermetter.   

Abstract

We prepared lipoprotein (a) and LDL covalently labeled with either BODIPY or rhodamine. A dual wavelength method was used for the microscopic observation of both lipoproteins during their interaction with HepG2 cells. Since a large proportion of Lp(a) colocalized with LDL on the cell surface and inside the cells, it was concluded that Lp(a) uptake into cells is mediated by LDL via internalization of LDL.

Entities:  

Year:  1994        PMID： 24233606     DOI： 10.1007/BF01881447

Source DB:  PubMed          Journal:  J Fluoresc        ISSN： 1053-0509            Impact factor:   2.217


  8 in total

1.  Biologically active fluorescent derivatives of spinach calmodulin that report calmodulin target protein binding.

Authors:  J S Mills; M P Walsh; K Nemcek; J D Johnson
Journal:  Biochemistry       Date:  1988-02-09       Impact factor: 3.162

Review 2.  Lipoprotein (a). Heterogeneity and biological relevance.

Authors:  A M Scanu; G M Fless
Journal:  J Clin Invest       Date:  1990-06       Impact factor: 14.808

3.  Lipoprotein(a) binding to other apolipoprotein B containing lipoproteins.

Authors:  V N Trieu; W J McConathy
Journal:  Biochemistry       Date:  1990-06-26       Impact factor: 3.162

Review 4.  The mysteries of lipoprotein(a).

Authors:  G Utermann
Journal:  Science       Date:  1989-11-17       Impact factor: 47.728

5.  Fluorescent membrane probes incorporating dipyrrometheneboron difluoride fluorophores.

Authors:  I D Johnson; H C Kang; R P Haugland
Journal:  Anal Biochem       Date:  1991-11-01       Impact factor: 3.365

6.  Organization of phosphatidylcholine and sphingomyelin in the surface monolayer of low density lipoprotein and lipoprotein(a) as determined by time-resolved fluorometry.

Authors:  A Sommer; E Prenner; R Gorges; H Stütz; H Grillhofer; G M Kostner; F Paltauf; A Hermetter
Journal:  J Biol Chem       Date:  1992-12-05       Impact factor: 5.157

7.  Lipoprotein(a) mediates high affinity low density lipoprotein association to receptor negative fibroblasts.

Authors:  G M Kostner; H K Grillhofer
Journal:  J Biol Chem       Date:  1991-11-05       Impact factor: 5.157

8.  Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts.

Authors:  L S Barak; W W Webb
Journal:  J Cell Biol       Date:  1981-09       Impact factor: 10.539
  8 in total

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