INTRODUCTION: Synovial sarcomas of the spine are very rare, most rare of which was occurring in the thoracic vertebral body. The diagnosis of synovial sarcomas was very difficult. It depends on the radiological examination, immunohistochemical examination and gene examination. The best treatment to them was completely surgical resection with negative margins. Other treatments such as radiation therapy and chemotherapy were just adjuvant. The prognosis of synovial sarcomas was disappointing. CASE PRESENTATION: A 26-year-old male patient had low back pain. The radiological examination showed bony erosion of the T7 vertebral body and no soft tissue mass around the spine. He underwent T7 resection en bloc and internal fixation with two levels above T7 and two levels below T7. Then histopathological and gene examination revealed high malignant synovial sarcoma. So he was treated by chemotherapy and external beam radiation therapy after surgery. CONCLUSION: Primary vertebral body synovial sarcoma is very rare and difficult to diagnose and treat.
INTRODUCTION:Synovial sarcomas of the spine are very rare, most rare of which was occurring in the thoracic vertebral body. The diagnosis of synovial sarcomas was very difficult. It depends on the radiological examination, immunohistochemical examination and gene examination. The best treatment to them was completely surgical resection with negative margins. Other treatments such as radiation therapy and chemotherapy were just adjuvant. The prognosis of synovial sarcomas was disappointing. CASE PRESENTATION: A 26-year-old male patient had low back pain. The radiological examination showed bony erosion of the T7 vertebral body and no soft tissue mass around the spine. He underwent T7 resection en bloc and internal fixation with two levels above T7 and two levels below T7. Then histopathological and gene examination revealed high malignant synovial sarcoma. So he was treated by chemotherapy and external beam radiation therapy after surgery. CONCLUSION:Primary vertebral body synovial sarcoma is very rare and difficult to diagnose and treat.
Authors: Sang-il Suh; Hae Young Seol; Suk-Joo Hong; Joo Han Kim; Jong Hyun Kim; Ju Han Lee; Myung Gyu Kim Journal: AJNR Am J Neuroradiol Date: 2005-10 Impact factor: 3.825
Authors: Jefferson Terry; Tsuyoshi Saito; Subbaya Subramanian; Cindy Ruttan; Cristina R Antonescu; John R Goldblum; Erinn Downs-Kelly; Christopher L Corless; Brian P Rubin; Matt van de Rijn; Marc Ladanyi; Torsten O Nielsen Journal: Am J Surg Pathol Date: 2007-02 Impact factor: 6.394
Authors: Torsten O Nielsen; Rob B West; Sabine C Linn; Orly Alter; Margaret A Knowling; John X O'Connell; Shirley Zhu; Mike Fero; Gavin Sherlock; Jonathan R Pollack; Patrick O Brown; David Botstein; Matt van de Rijn Journal: Lancet Date: 2002-04-13 Impact factor: 79.321