Literature DB >> 24232374

Neurodegenerative disease: Tau immunotherapy targets transcellular propagation.

Monica Hoyos Flight.   

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Year:  2013        PMID： 24232374     DOI： 10.1038/nrd4179

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  1 in total

1.  Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

Authors:  Marc I Diamond; David M Holtzman; Kiran Yanamandra; Najla Kfoury; Hong Jiang; Thomas E Mahan; Shengmei Ma; Susan E Maloney; David F Wozniak
Journal:  Neuron       Date:  2013-09-26       Impact factor: 17.173
  1 in total
  3 in total

1.  Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies.

Authors:  Chun-ling Dai; Xia Chen; Syed Faraz Kazim; Fei Liu; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal
Journal:  J Neural Transm (Vienna)       Date:  2014-09-19       Impact factor: 3.575

2.  Tau passive immunization inhibits not only tau but also Aβ pathology.

Authors:  Chun-Ling Dai; Yunn Chyn Tung; Fei Liu; Cheng-Xin Gong; Khalid Iqbal
Journal:  Alzheimers Res Ther       Date:  2017-01-10       Impact factor: 6.982

Review 3.  Molecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation.

Authors:  Masato Hasegawa
Journal:  Biomolecules       Date:  2016-04-28
  3 in total

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