| Literature DB >> 24231656 |
Elie J Diner1, Russell E Vance2.
Abstract
Detection of cytosolic DNA activates a downstream signaling molecule called STimulator of INterferon Genes (STING). Inappropriate or excessive activation of STING can lead to autoimmune disease. A new paper in Cell addresses the important question of how STING-dependent signaling is normally constrained.Entities:
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Year: 2013 PMID： 24231656 DOI： 10.1016/j.it.2013.10.011
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687