Literature DB >> 2423155

[Transplacental carcinogenic effect of the serotonin derivative 5-methoxyindoleacetic acid].

N V Malakhova, M O Raushenbakh.   

Abstract

Transplacental administration of serotonin metabolite 5-methoxyindole-3-acetic acid possessing blastomogenic activity induced the development of malignant and benign neoplasms (lymphosarcomas, adenomas, hepatomas and other tumours) in 84% of C57BL/6 mouse progeny. The number of neoplasms was significantly higher, than in the control, they appeared earlier and were more malignant.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 2423155

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN: 0365-9615


  1 in total

1.  NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium.

Authors:  Jose Manuel Sánchez-Maldonado; Manuel Martínez-Bueno; Helena Canhão; Rob Ter Horst; Sonia Muñoz-Peña; Ana Moñiz-Díez; Ana Rodríguez-Ramos; Alejandro Escudero; Signe B Sorensen; Merete L Hetland; Miguel A Ferrer; Bente Glintborg; Ileana Filipescu; Eva Pérez-Pampin; Pablo Conesa-Zamora; Antonio García; Alfons den Broeder; Salvatore De Vita; Svend Erik Hove Jacobsen; Eduardo Collantes; Luca Quartuccio; Mihai G Netea; Yang Li; João E Fonseca; Manuel Jurado; Miguel Ángel López-Nevot; Marieke J H Coenen; Vibeke Andersen; Rafael Cáliz; Juan Sainz
Journal:  Sci Rep       Date:  2020-03-09       Impact factor: 4.379

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.