Literature DB >> 24231167

Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems.

Devon Carroll1, Victoria Hallett, Christopher J McDougle, Michael G Aman, James T McCracken, Elaine Tierney, L Eugene Arnold, Denis G Sukhodolsky, Luc Lecavalier, Benjamin L Handen, Naomi Swiezy, Cynthia Johnson, Karen Bearss, Benedetto Vitiello, Lawrence Scahill.   

Abstract

This study identified subtypes of aggression in a sample of 206 children with autism spectrum disorder (ASD) who participated in 2 risperidone trials. The narratives were derived from a parent interview about each child's 2 most pressing problems. Five subtypes of aggression emerged: hot aggression only, cold aggression only, self-injurious behavior (SIB) only, aggression and SIB, and nonaggressive. All groups showed a high rate of positive response to risperidone with no differences across subtypes. These study findings extend understanding of aggression in ASD and may be useful to guide further study on biological mechanisms and individualized treatment in ASD.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aggression; Autism; Disruptive behavior; Self-injury

Mesh:

Substances:

Year:  2014        PMID: 24231167      PMCID: PMC4212264          DOI: 10.1016/j.chc.2013.08.002

Source DB:  PubMed          Journal:  Child Adolesc Psychiatr Clin N Am        ISSN: 1056-4993


  35 in total

1.  Children's Yale-Brown Obsessive Compulsive Scale: reliability and validity.

Authors:  L Scahill; M A Riddle; M McSwiggin-Hardin; S I Ort; R A King; W K Goodman; D Cicchetti; J F Leckman
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1997-06       Impact factor: 8.829

2.  Reactive and proactive aggression in school children and psychiatrically impaired chronically assaultive youth.

Authors:  K A Dodge; J E Lochman; J D Harnish; J E Bates; G S Pettit
Journal:  J Abnorm Psychol       Date:  1997-02

3.  Toward a functional analysis of self-injury.

Authors:  B A Iwata; M F Dorsey; K J Slifer; K E Bauman; G S Richman
Journal:  J Appl Behav Anal       Date:  1994

Review 4.  Subtypes of aggression and their relevance to child psychiatry.

Authors:  B Vitiello; D M Stoff
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1997-03       Impact factor: 8.829

5.  Diagnosing autism: analyses of data from the Autism Diagnostic Interview.

Authors:  C Lord; A Pickles; J McLennan; M Rutter; J Bregman; S Folstein; E Fombonne; M Leboyer; N Minshew
Journal:  J Autism Dev Disord       Date:  1997-10

Review 6.  Reactive and proactive aggression in children--a review of theory, findings and the relevance for child and adolescent psychiatry.

Authors:  Maaike Kempes; Walter Matthys; Han de Vries; Herman van Engeland
Journal:  Eur Child Adolesc Psychiatry       Date:  2005-02       Impact factor: 4.785

7.  Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder.

Authors:  Randall Owen; Linmarie Sikich; Ronald N Marcus; Patricia Corey-Lisle; George Manos; Robert D McQuade; William H Carson; Robert L Findling
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8.  Trial design challenges when combining medication and parent training in children with pervasive developmental disorders.

Authors:  Lawrence Scahill; Michael G Aman; Christopher J McDougle; L Eugene Arnold; James T McCracken; Benjamin Handen; Cynthia Johnson; James Dziura; Eric Butter; Denis Sukhodolsky; Naomi Swiezy; James Mulick; Kimberly Stigler; Karen Bearss; Louise Ritz; Ann Wagner; Benedetto Vitiello
Journal:  J Autism Dev Disord       Date:  2008-12-19

9.  Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents.

Authors:  Christoph U Correll; Peter Manu; Vladimir Olshanskiy; Barbara Napolitano; John M Kane; Anil K Malhotra
Journal:  JAMA       Date:  2009-10-28       Impact factor: 56.272

10.  A placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder.

Authors:  Ronald N Marcus; Randall Owen; Lisa Kamen; George Manos; Robert D McQuade; William H Carson; Michael G Aman
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2009-11       Impact factor: 8.829

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  12 in total

1.  Using a Patient-Centered Outcome Measure to Test Methylphenidate Versus Placebo in Children with Autism Spectrum Disorder.

Authors:  Lawrence Scahill; Karen Bearss; Rena Sarhangian; Christopher J McDougle; L Eugene Arnold; Michael G Aman; James T McCracken; Elaine Tierney; Scott Gillespie; Valentina Postorino; Benedetto Vitiello
Journal:  J Child Adolesc Psychopharmacol       Date:  2016-11-28       Impact factor: 2.576

2.  Injury Mortality in Individuals With Autism.

Authors:  Joseph Guan; Guohua Li
Journal:  Am J Public Health       Date:  2017-03-21       Impact factor: 9.308

Review 3.  Management of Self-injurious Behaviors in Children with Neurodevelopmental Disorders: A Pharmacotherapy Overview.

Authors:  Ashley Sabus; James Feinstein; Patrick Romani; Edward Goldson; Allison Blackmer
Journal:  Pharmacotherapy       Date:  2019-03-27       Impact factor: 4.705

4.  Factors Associated with Self-Injurious Behaviors in Children with Autism Spectrum Disorder: Findings from Two Large National Samples.

Authors:  G N Soke; S A Rosenberg; R F Hamman; T Fingerlin; C R Rosenberg; L Carpenter; L C Lee; E Giarelli; L D Wiggins; M S Durkin; A Reynolds; C DiGuiseppi
Journal:  J Autism Dev Disord       Date:  2017-02

Review 5.  Are Molecules Involved in Neuritogenesis and Axon Guidance Related to Autism Pathogenesis?

Authors:  Jan Bakos; Zuzana Bacova; Stephen G Grant; Ana M Castejon; Daniela Ostatnikova
Journal:  Neuromolecular Med       Date:  2015-05-20       Impact factor: 3.843

6.  Development and Psychometric Evaluation of the Open-Source Challenging Behavior Scale (OS-CBS).

Authors:  Thomas W Frazier; Izma Khaliq; Keeley Scullin; Mirko Uljarevic; Andy Shih; Arun Karpur
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7.  Relationship between brain stem volume and aggression in children diagnosed with autism spectrum disorder.

Authors:  Rebecca A Lundwall; Kevin G Stephenson; E Shannon Neeley-Tass; Jonathan C Cox; Mikle South; Erin D Bigler; Emily Anderberg; Molly D Prigge; Blake D Hansen; Janet E Lainhart; Ryan O Kellems; Jo Ann Petrie; Terisa P Gabrielsen
Journal:  Res Autism Spectr Disord       Date:  2016-12-09

8.  Self-injurious behaviors in children with autism spectrum disorder enrolled in the Study to Explore Early Development.

Authors:  Gnakub Norbert Soke; Steven A Rosenberg; Cordelia Robinson Rosenberg; Roma A Vasa; Li-Ching Lee; Carolyn DiGuiseppi
Journal:  Autism       Date:  2017-06-21

9.  Sibling Death after Being Thrown from Window by Brother with Autism: Defenestration, an Emerging High-Risk Behavior.

Authors:  Osman Sabuncuoglu; Mustafa Yasin Irmak; Nagehan Ucok Demir; Duygu Murat; Can Tumba; Yuksel Yilmaz
Journal:  Case Rep Psychiatry       Date:  2015-08-03

10.  Lurasidone for the Treatment of Irritability Associated with Autistic Disorder.

Authors:  Antony Loebel; Matthew Brams; Robert S Goldman; Robert Silva; David Hernandez; Ling Deng; Raymond Mankoski; Robert L Findling
Journal:  J Autism Dev Disord       Date:  2016-04
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