| Literature DB >> 24229706 |
Luca Tamagnone1, Michael Rehman.
Abstract
Sema3E, a ligand for PlexinD1, controls angiogenesis and promotes cancer invasion and metastasis. In this issue of Cancer Cell, Luchino and colleagues report that Sema3E also ensures breast cancer cell viability by blocking a previously unknown proapoptotic signaling cascade elicited by unliganded PlexinD1, thus behaving as a "dependence receptor."Entities:
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Year: 2013 PMID: 24229706 DOI: 10.1016/j.ccr.2013.10.010
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743