| Literature DB >> 24229703 |
Tsz Kan Fung1, Anskar Yu Hung Leung, Chi Wai Eric So.
Abstract
Although CEBPA mutations are among the most common genetic abnormalities in acute myeloid leukemia (AML), the transformation mechanism remains largely obscure. In this issue of Cancer Cell, Zhang and colleagues report that SOX4 is a direct target and crucial mediator of C/EBPα mutants in AML, revealing a potential therapeutic avenue.Entities:
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Year: 2013 PMID： 24229703 DOI： 10.1016/j.ccr.2013.10.016
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743