Literature DB >> 24228486

[Effect of a complex preparation of sea urchin shells on blood glucose level and oxidative stress parameters in type II diabetes model].

M A Kovaleva, S A Ivanova, M N Makarova, O N Pozharitskaia, A N Shikov, V G Makarov.   

Abstract

The experimental preclinical study on mice showed that a complex of polyhydroxylated naphthoquinone pigments and minerals from shells of sea urchins decreases the concentration of glucose, stimulates the synthesis of phospholipids in liver, and has antioxidant properties. On the model of streptozotocin-nicotinamide-induced type II diabetes, this complex of polyhydroxylated naphthoquinone pigments and minerals from sea urchin shells exhibited activity after administration for 10 days in a dose of 1.8 mg/kg.

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Year:  2013        PMID: 24228486

Source DB:  PubMed          Journal:  Eksp Klin Farmakol        ISSN: 0869-2092


  3 in total

1.  Chemical Profiling and Bioactivity of Body Wall Lipids from Strongylocentrotus droebachiensis.

Authors:  Alexander N Shikov; Into Laakso; Olga N Pozharitskaya; Tuulikki Seppänen-Laakso; Anna S Krishtopina; Marina N Makarova; Heikki Vuorela; Valery Makarov
Journal:  Mar Drugs       Date:  2017-11-24       Impact factor: 5.118

2.  The Roles of Spinochromes in Four Shallow Water Tropical Sea Urchins and Their Potential as Bioactive Pharmacological Agents.

Authors:  Lola Brasseur; Elise Hennebert; Laurence Fievez; Guillaume Caulier; Fabrice Bureau; Lionel Tafforeau; Patrick Flammang; Pascal Gerbaux; Igor Eeckhaut
Journal:  Mar Drugs       Date:  2017-06-16       Impact factor: 5.118

3.  Multi-target bioactivity of summer quinones production in the Persian Gulf burrowing black-type sea urchin.

Authors:  Soolmaz Soleimani; Sakineh Mashjoor; Morteza Yousefzadi; Manish Kumar
Journal:  Heliyon       Date:  2022-03-04
  3 in total

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