Literature DB >> 2422800

[Results of the study of the activity of bone marrow nucleolar organizers in patients with multiple myeloma].

N N Mamaev, S E Mamaeva, E A Ushakova, I L Liburkina, E I Pozniak.   

Abstract

Data obtained from karyotyping and estimation of nucleolar organizer (NO) activity in bone marrow cells from 9 patients with multiple myeloma (MM) and from 8 donors are presented. Chromosomes of the 14th and 1st pairs in patients with MM are confirmed to be more frequently involved in rearrangements. It is proved that activity of NO in myeloma cells is rather high as compared to that of erythroid and granulocyte cells, that is associated with their participation in paraprotein synthesis.

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Year:  1986        PMID: 2422800

Source DB:  PubMed          Journal:  Tsitol Genet        ISSN: 0564-3783


  1 in total

1.  Age related decrease of NOR activity in bone marrow metaphase chromosomes from healthy individuals.

Authors:  E Pedrazzini; N Mamaev; I Slavutsky
Journal:  Mol Pathol       Date:  1998-02
  1 in total

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