Literature DB >> 24227987

Secondary glaucoma as initial manifestation of uveal melanoma.

Ihab Saad Othman1, Maher Assem, Iman M A Zaki.   

Abstract

PURPOSE: Secondary glaucoma can be induced by a variety of local ocular problems. Intraocular tumors may initially present as secondary glaucoma.
METHODS: 8 consecutive patients with secondary glaucoma were found to have uveal melanoma. Thorough examination included detailed history, fundus examination with scleral depression, B scan ultrasonography, and CT/MRI scanning techniques.
RESULTS: A single case presented with spontaneous hyphema, two patients presented with secondary glaucoma, extraocular melanoma and metastases, a single case was found to have angle block by an iridociliary ring melanoma and 4 cases presented with neovascular glaucoma. Enucleation was necessary in all 8 cases.
CONCLUSIONS: General ophthalmologists should be aware of these rare initial manifestations of intraocular tumors as secondary glaucoma. Enucleation would be recommended in most cases of intraocular malignancy manifesting as secondary glaucoma. One should be extremely cautious in doing a penetrating surgery in such cases.

Entities:  

Keywords:  Glaucoma; Melanoma; Neovascular glaucoma; Orbital melanoma

Year:  2013        PMID: 24227987      PMCID: PMC3770216          DOI: 10.1016/j.sjopt.2013.07.004

Source DB:  PubMed          Journal:  Saudi J Ophthalmol        ISSN: 1319-4534


  22 in total

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2.  Small choroidal melanoma with massive extraocular extension: invasion through posterior scleral emissary channels.

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3.  Red laser cyclophotocoagulation in the treatment of secondary glaucoma in eyes with uveal melanoma.

Authors:  Anni Piirtola; Päivi Puska; Tero Kivelä
Journal:  J Glaucoma       Date:  2014-01       Impact factor: 2.503

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Journal:  Br J Ophthalmol       Date:  2001-06       Impact factor: 4.638

5.  Ring melanoma of the anterior chamber angle: a report of fourteen cases.

Authors:  H Demirci; C L Shields; J A Shields; R C Eagle; S Honavar
Journal:  Am J Ophthalmol       Date:  2001-09       Impact factor: 5.258

6.  Uveal melanoma presenting as acute angle-closure glaucoma: report of two cases.

Authors:  Erika Escalona-Benz; Matthew S Benz; Jonathan W Briggs; Donald L Budenz; Richard K Parrish; Timothy G Murray
Journal:  Am J Ophthalmol       Date:  2003-10       Impact factor: 5.258

7.  [Ring melanoma revealed by spontaneous hyphema].

Authors:  N Abi-Ayad; J D Grange; E Watkin; M De Bats; J Fleury; L Kodjikian; J Gambrelle
Journal:  J Fr Ophtalmol       Date:  2007-09       Impact factor: 0.818

8.  Prevalence and mechanisms of secondary intraocular pressure elevation in eyes with intraocular tumors.

Authors:  C L Shields; J A Shields; M B Shields; J J Augsburger
Journal:  Ophthalmology       Date:  1987-07       Impact factor: 12.079

9.  Choroidal melanoma presenting as vitreous haemorrhage.

Authors:  I A Cunliffe; I G Rennie
Journal:  Eye (Lond)       Date:  1993       Impact factor: 3.775

10.  Ciliary body melanoma masquerading as chronic uveitis.

Authors:  Q D Nguyen; C S Foster
Journal:  Ocul Immunol Inflamm       Date:  1998-12       Impact factor: 3.070

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  5 in total

Review 1.  Secondary glaucoma as initial manifestation of ring melanoma: a case report and review of literature.

Authors:  Manli Zhao; Yalin Mu; Yalong Dang; Yu Zhu
Journal:  Int J Clin Exp Pathol       Date:  2014-10-15

2.  Whole-genome sequencing unravels novel genetic determinants and regulatory pathways associated with triamcinolone acetonide-induced ocular hypertension.

Authors:  Lakshmi Badrinarayanan; Hemavathy Nagarajan; Pukhraj Rishi; Ekta Rishi; Ronnie Jacob George; Srujana Chitipothu
Journal:  Mol Genet Genomics       Date:  2022-10-12       Impact factor: 2.980

Review 3.  Neovascular glaucoma: a review.

Authors:  Gustavo B Rodrigues; Ricardo Y Abe; Camila Zangalli; Savio L Sodre; Flavia A Donini; Danilo C Costa; Andre Leite; Joao P Felix; Marcelo Torigoe; Alberto Diniz-Filho; Homero Gusmão de Almeida
Journal:  Int J Retina Vitreous       Date:  2016-11-14

4.  Uveal Melanoma and Secondary Angle-Closure Crisis: A Case Report and Literature Review.

Authors:  Tung Thanh Hoang; Tuan Anh Hoang; Peter McCluskey; John Grigg
Journal:  Case Rep Ophthalmol       Date:  2021-06-08

5.  Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma.

Authors:  Yewlin E Chee; Raghu Mudumbai; Steven S Saraf; Thellea Leveque; Verena S Grieco; Monique A Mogensen; Rebecca A Yoda; Luis F Gonzalez-Cuyar; Andrew W Stacey
Journal:  Am J Ophthalmol Case Rep       Date:  2021-07-22
  5 in total

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