Literature DB >> 24227857

Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point.

Catherine Riou1, Wendy A Burgers, Koleka Mlisana, Richard A Koup, Mario Roederer, Salim S Abdool Karim, Carolyn Williamson, Clive M Gray.   

Abstract

Defining the characteristics of HIV-specific CD8(+) T cell responses that lead to viral control is crucial for vaccine development. We evaluated the differential impact of magnitude, polyfunctional capacity, and specificity of the CD8(+) response at approximately 6 months postinfection on the viral set point at 12 months in a cohort of HIV-infected individuals. High frequencies of Gag and Nef responses endowed with four functions were the best predictors of a low viral set point.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24227857      PMCID： PMC3911608          DOI： 10.1128/JVI.02968-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  31 in total

1.  Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.

Authors:  Michael K P Liu; Natalie Hawkins; Adam J Ritchie; Vitaly V Ganusov; Victoria Whale; Simon Brackenridge; Hui Li; Jeffrey W Pavlicek; Fangping Cai; Melissa Rose-Abrahams; Florette Treurnicht; Peter Hraber; Catherine Riou; Clive Gray; Guido Ferrari; Rachel Tanner; Li-Hua Ping; Jeffrey A Anderson; Ronald Swanstrom; Myron Cohen; Salim S Abdool Karim; Barton Haynes; Persephone Borrow; Alan S Perelson; George M Shaw; Beatrice H Hahn; Carolyn Williamson; Bette T Korber; Feng Gao; Steve Self; Andrew McMichael; Nilu Goonetilleke
Journal:  J Clin Invest       Date:  2012-12-10       Impact factor: 14.808

2.  Escape from CD8(+) T cell responses in Mamu-B*00801(+) macaques differentiates progressors from elite controllers.

Authors:  Philip A Mudd; Adam J Ericsen; Benjamin J Burwitz; Nancy A Wilson; David H O'Connor; Austin L Hughes; David I Watkins
Journal:  J Immunol       Date:  2012-03-02       Impact factor: 5.422

3.  Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B 2705-restricted CD8+ T cells.

Authors:  Rebecca P Payne; Henrik Kløverpris; Jonah B Sacha; Zabrina Brumme; Chanson Brumme; Søren Buus; Stuart Sims; Stephen Hickling; Lynn Riddell; Fabian Chen; Graz Luzzi; Anne Edwards; Rodney Phillips; Julia G Prado; Philip J R Goulder
Journal:  J Virol       Date:  2010-08-04       Impact factor: 5.103

Review 4.  Vaccine design for CD8 T lymphocyte responses.

Authors:  Richard A Koup; Daniel C Douek
Journal:  Cold Spring Harb Perspect Med       Date:  2011-09       Impact factor: 6.915

5.  Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.

Authors:  Adam R Hersperger; Florencia Pereyra; Martha Nason; Korey Demers; Prameet Sheth; Lucy Y Shin; Colin M Kovacs; Benigno Rodriguez; Scott F Sieg; Leia Teixeira-Johnson; Debbie Gudonis; Paul A Goepfert; Michael M Lederman; Ian Frank; George Makedonas; Rupert Kaul; Bruce D Walker; Michael R Betts
Journal:  PLoS Pathog       Date:  2010-05-27       Impact factor: 6.823

6.  Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

Authors:  M M Addo; X G Yu; A Rathod; D Cohen; R L Eldridge; D Strick; M N Johnston; C Corcoran; A G Wurcel; C A Fitzpatrick; M E Feeney; W R Rodriguez; N Basgoz; R Draenert; David R Stone; C Brander; P J R Goulder; E S Rosenberg; M Altfeld; B D Walker
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

7.  Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques.

Authors:  Melisa L Budde; Justin M Greene; Emily N Chin; Adam J Ericsen; Matthew Scarlotta; Brian T Cain; Ngoc H Pham; Ericka A Becker; Max Harris; Jason T Weinfurter; Shelby L O'Connor; Michael Piatak; Jeffrey D Lifson; Emma Gostick; David A Price; Thomas C Friedrich; David H O'Connor
Journal:  J Virol       Date:  2012-05-09       Impact factor: 5.103

8.  Definition of the viral targets of protective HIV-1-specific T cell responses.

Authors:  Beatriz Mothe; Anuska Llano; Javier Ibarrondo; Marcus Daniels; Cristina Miranda; Jennifer Zamarreño; Vanessa Bach; Rosario Zuniga; Susana Pérez-Álvarez; Christoph T Berger; Maria C Puertas; Javier Martinez-Picado; Morgane Rolland; Marilu Farfan; James J Szinger; William H Hildebrand; Otto O Yang; Victor Sanchez-Merino; Chanson J Brumme; Zabrina L Brumme; David Heckerman; Todd M Allen; James I Mullins; Guadalupe Gómez; Philip J Goulder; Bruce D Walker; Jose M Gatell; Bonaventura Clotet; Bette T Korber; Jorge Sanchez; Christian Brander
Journal:  J Transl Med       Date:  2011-12-07       Impact factor: 5.531

9.  CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control.

Authors:  Beatriz Mothe; Anuska Llano; Javier Ibarrondo; Jennifer Zamarreño; Mattia Schiaulini; Cristina Miranda; Marta Ruiz-Riol; Christoph T Berger; M José Herrero; Eduard Palou; Montse Plana; Morgane Rolland; Ashok Khatri; David Heckerman; Florencia Pereyra; Bruce D Walker; David Weiner; Roger Paredes; Bonaventura Clotet; Barbara K Felber; George N Pavlakis; James I Mullins; Christian Brander
Journal:  PLoS One       Date:  2012-01-04       Impact factor: 3.240

10.  Antiviral inhibitory capacity of CD8+ T cells predicts the rate of CD4+ T-cell decline in HIV-1 infection.

Authors:  Hongbing Yang; Hao Wu; Gemma Hancock; Genevieve Clutton; Nellia Sande; Xiaoning Xu; Huiping Yan; Xiaojie Huang; Brian Angus; Kristin Kuldanek; Sarah Fidler; Thomas N Denny; Jacqueline Birks; Andrew McMichael; Lucy Dorrell
Journal:  J Infect Dis       Date:  2012-06-18       Impact factor: 5.226
View more
  22 in total

1.  T Regulatory Cell Induced Foxp3 Binds the IL2, IFNγ, and TNFα Promoters in Virus-Specific CD8+ T Cells from Feline Immunodeficiency Virus Infected Cats.

Authors:  Yan Wang; Mukta Nag; Joanne L Tuohy; Kristina De Paris; Jonathan E Fogle
Journal:  AIDS Res Hum Retroviruses       Date:  2017-11-17       Impact factor: 2.205

2.  Ineffectual targeting of HIV-1 Nef by cytotoxic T lymphocytes in acute infection results in no functional impairment or viremia reduction.

Authors:  Justin De La Cruz; Thomas Vollbrecht; Patricia Frohnen; Hwee L Ng; Eric S Daar; Otto O Yang; Martha J Lewis
Journal:  J Virol       Date:  2014-04-30       Impact factor: 5.103

Review 3.  Preserving HIV-specific T cell responses: does timing of antiretroviral therapy help?

Authors:  Bernard J C Macatangay; Charles R Rinaldo
Journal:  Curr Opin HIV AIDS       Date:  2015-01       Impact factor: 4.283

4.  Impaired Nef function is associated with early control of HIV-1 viremia.

Authors:  Xiaomei T Kuang; Xiaoguang Li; Gursev Anmole; Philip Mwimanzi; Aniqa Shahid; Anh Q Le; Louise Chong; Hua Qian; Toshiyuki Miura; Tristan Markle; Bemuluyigza Baraki; Elizabeth Connick; Eric S Daar; Heiko Jessen; Anthony D Kelleher; Susan Little; Martin Markowitz; Florencia Pereyra; Eric S Rosenberg; Bruce D Walker; Takamasa Ueno; Zabrina L Brumme; Mark A Brockman
Journal:  J Virol       Date:  2014-06-25       Impact factor: 5.103

5.  Rapid disease progression in HIV-1 subtype C-infected South African women.

Authors:  Koleka Mlisana; Lise Werner; Nigel J Garrett; Lyle R McKinnon; Francois van Loggerenberg; Jo-Ann S Passmore; Clive M Gray; Lynn Morris; Carolyn Williamson; Salim S Abdool Karim
Journal:  Clin Infect Dis       Date:  2014-07-17       Impact factor: 9.079

6.  Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1-Infected Apoptotic Cells.

Authors:  Bernard J C Macatangay; Sharon A Riddler; Nicole D Wheeler; Jonathan Spindler; Mariam Lawani; Feiyu Hong; Mary J Buffo; Theresa L Whiteside; Mary F Kearney; John W Mellors; Charles R Rinaldo
Journal:  J Infect Dis       Date:  2015-12-08       Impact factor: 5.226

Review 7.  Challenges in the design of a T cell vaccine in the context of HIV-1 diversity.

Authors:  Marcel Tongo; Wendy A Burgers
Journal:  Viruses       Date:  2014-10-23       Impact factor: 5.048

8.  HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

Authors:  Victor Y Du; Anju Bansal; Jonathan Carlson; Jesus F Salazar-Gonzalez; Maria G Salazar; Kristin Ladell; Stephanie Gras; Tracy M Josephs; Sonya L Heath; David A Price; Jamie Rossjohn; Eric Hunter; Paul A Goepfert
Journal:  J Immunol       Date:  2016-03-16       Impact factor: 5.422

9.  The APPEESFRS Peptide, Restricted by the HLA-B*35:01 Molecule, and the APPEESFRF Variant Derived from an Autologous HIV-1 Strain Induces Polyfunctional Responses in CD8+ T Cells.

Authors:  Liliana Acevedo-Sáenz; Liseth Carmona-Pérez; Paula Andrea Velilla-Hernández; Julio C Delgado; María Teresa Rugeles L
Journal:  Biores Open Access       Date:  2015-01-01

10.  Early skewed distribution of total and HIV-specific CD8+ T-cell memory phenotypes during primary HIV infection is related to reduced antiviral activity and faster disease progression.

Authors:  Yanina Ghiglione; Juliana Falivene; María Julia Ruiz; Natalia Laufer; María Eugenia Socías; Pedro Cahn; Luis Giavedoni; Omar Sued; María Magdalena Gherardi; Horacio Salomón; Gabriela Turk
Journal:  PLoS One       Date:  2014-08-05       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.