Literature DB >> 24226293

Latest developments in the imaging of fibrotic liver disease.

Minal J Sangwaiya1, David I N Sherman2, David J Lomas3, Philip J Shorvon4.   

Abstract

According to the World Health Organization, liver cirrhosis accounted for 1.8% of all deaths in Europe, causing about 170,000 deaths per year. Approximately 29 million persons in the EU suffer from chronic liver disease and this trend is on the rise. Liver disease is the EU's fifth most common cause of death accounting for at least one in six deaths. Early detection and monitoring of fibrosis has the potential to direct management of these chronic liver diseases and avert morbidity and mortality. Although the available techniques are in their infancy and the very early stages of fibrosis are difficult to detect, there have been significant advances in imaging over the last decade that has resulted in the use of these new imaging techniques being introduced into the patient pathway. This review explores the accuracies of these imaging techniques, their role in the management of patients, and the potential for the future. © The Foundation Acta Radiologica 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Entities:  

Keywords:  Abdomen/GI; fibrosis; liver

Mesh:

Substances:

Year:  2013        PMID: 24226293     DOI: 10.1177/0284185113510159

Source DB:  PubMed          Journal:  Acta Radiol        ISSN: 0284-1851            Impact factor:   1.990


  3 in total

Review 1.  Non-invasive diagnosis of liver fibrosis and cirrhosis.

Authors:  Yoav Lurie; Muriel Webb; Ruth Cytter-Kuint; Shimon Shteingart; Gerardo Z Lederkremer
Journal:  World J Gastroenterol       Date:  2015-11-07       Impact factor: 5.742

2.  Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver.

Authors:  Alyssa Charrier; Ruju Chen; Li Chen; Sherri Kemper; Takako Hattori; Masaharu Takigawa; David R Brigstock
Journal:  Surgery       Date:  2014-06-02       Impact factor: 3.982

Review 3.  Fibrosis imaging: Current concepts and future directions.

Authors:  Maike Baues; Anshuman Dasgupta; Josef Ehling; Jai Prakash; Peter Boor; Frank Tacke; Fabian Kiessling; Twan Lammers
Journal:  Adv Drug Deliv Rev       Date:  2017-11-20       Impact factor: 15.470

  3 in total

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