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Literature DB >> 24226193

Immunity, inflammation and cancer: a leading role for adenosine.

Luca Antonioli¹, Corrado Blandizzi, Pál Pacher, György Haskó.

Abstract

Cancer is a complex disease that is dictated by both cancer cell-intrinsic and cell-extrinsic processes. Adenosine is an ancient extracellular signalling molecule that can regulate almost all aspects of tissue function. As such, several studies have recently highlighted a crucial role for adenosine signalling in regulating the various aspects of cell-intrinsic and cell-extrinsic processes of cancer development. This Review critically discusses the role of adenosine and its receptors in regulating the complex interplay among immune, inflammatory, endothelial and cancer cells during the course of neoplastic disease.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2013 PMID： 24226193 DOI： 10.1038/nrc3613

Source DB: PubMed Journal: Nat Rev Cancer ISSN： 1474-175X Impact factor: 60.716

214 in total

1. A2A adenosine receptor protects tumors from antitumor T cells.

Authors: Akio Ohta; Elieser Gorelik; Simon J Prasad; Franca Ronchese; Dmitriy Lukashev; Michael K K Wong; Xiaojun Huang; Sheila Caldwell; Kebin Liu; Patrick Smith; Jiang-Fan Chen; Edwin K Jackson; Sergey Apasov; Scott Abrams; Michail Sitkovsky
Journal: Proc Natl Acad Sci U S A Date: 2006-08-17 Impact factor: 11.205

2. Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3.

Authors: Mahmoud Aghaei; Fatemeh Karami-Tehrani; Mojtaba Panjehpour; Siamak Salami; Faranak Fallahian
Journal: Prostate Date: 2011-06-08 Impact factor: 4.104

3. A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells.

Authors: Eun-Jin Lee; Hye-Young Min; Hwa-Jin Chung; Eun-Jung Park; Dae-Hong Shin; Lak Shin Jeong; Sang Kook Lee
Journal: Biochem Pharmacol Date: 2005-09-15 Impact factor: 5.858

4. Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate.

Authors: Lili Feng; Xiaofeng Sun; Eva Csizmadia; Lihui Han; Shu Bian; Takashi Murakami; Xin Wang; Simon C Robson; Yan Wu
Journal: Neoplasia Date: 2011-03 Impact factor: 5.715

Review 5. Neutralizing tumor-promoting chronic inflammation: a magic bullet?

Authors: Lisa M Coussens; Laurence Zitvogel; A Karolina Palucka
Journal: Science Date: 2013-01-18 Impact factor: 47.728

6. HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia.

Authors: Meixiang Yang; Chunhong Ma; Shuxun Liu; Qianqian Shao; Wenjuan Gao; Bingfeng Song; Jintang Sun; Qi Xie; Yun Zhang; Alei Feng; Yanguo Liu; Weixu Hu; Xun Qu
Journal: Immunol Cell Biol Date: 2009-10-20 Impact factor: 5.126

Review 7. Molecular basis of metastasis.

Authors: Anne C Chiang; Joan Massagué
Journal: N Engl J Med Date: 2008-12-25 Impact factor: 91.245

8. Adenosine induces apoptosis in SBC-3 human lung cancer cells through A(3) adenosine receptor-dependent AMID upregulation.

Authors: Takeshi Kanno; Takashi Nakano; Yumiko Fujita; Akinobu Gotoh; Tomoyuki Nishizaki
Journal: Cell Physiol Biochem Date: 2012-07-31

Review 9. CD73 and adenosine generation in the creation of regulatory microenvironments.

Authors: F S Regateiro; S P Cobbold; H Waldmann
Journal: Clin Exp Immunol Date: 2013-01 Impact factor: 4.330

Review 10. Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

Authors: Céline Candé; Francesco Cecconi; Philippe Dessen; Guido Kroemer
Journal: J Cell Sci Date: 2002-12-15 Impact factor: 5.285

260 in total

1. Can respiratory hyperoxia mitigate adenosine-driven suppression of antitumor immunity?

Authors: Peter Vaupel; Arnulf Mayer
Journal: Ann Transl Med Date: 2015-11

2. Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages.

Authors: Fatemeh Momen-Heravi; Shashi Bala; Terence Bukong; Gyongyi Szabo
Journal: Nanomedicine Date: 2014-03-29 Impact factor: 5.307

Review 3. Inhibitors of the PD-1 Pathway in Tumor Therapy.

Authors: Martin W LaFleur; Yuki Muroyama; Charles G Drake; Arlene H Sharpe
Journal: J Immunol Date: 2018-01-15 Impact factor: 5.422

4. A2B adenosine receptor agonist induces cell cycle arrest and apoptosis in breast cancer stem cells via ERK1/2 phosphorylation.

Authors: Seyyed Mehdi Jafari; Hamid Reza Joshaghani; Mojtaba Panjehpour; Mahmoud Aghaei
Journal: Cell Oncol (Dordr) Date: 2017-12-07 Impact factor: 6.730