Literature DB >> 24225942

Piecing together the puzzle of severe malaria.

Aubrey J Cunnington1, Michael Walther, Eleanor M Riley.   

Abstract

Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.

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Year:  2013        PMID: 24225942     DOI: 10.1126/scitranslmed.3007432

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  22 in total

Review 1.  The role of PfEMP1 adhesion domain classification in Plasmodium falciparum pathogenesis research.

Authors:  Joseph D Smith
Journal:  Mol Biochem Parasitol       Date:  2014-07-23       Impact factor: 1.759

Review 2.  Biosensors for Detection of Human Placental Pathologies: A Review of Emerging Technologies and Current Trends.

Authors:  Jia Liu; Babak Mosavati; Andrew V Oleinikov; E Du
Journal:  Transl Res       Date:  2019-05-20       Impact factor: 7.012

Review 3.  Effects of type I interferons in malaria.

Authors:  Ismail Sebina; Ashraful Haque
Journal:  Immunology       Date:  2018-07-05       Impact factor: 7.397

4.  Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study.

Authors:  Arthur Mpimbaza; Grace Ndeezi; Anne Katahoire; Philip J Rosenthal; Charles Karamagi
Journal:  Am J Trop Med Hyg       Date:  2017-10-10       Impact factor: 2.345

Review 5.  Infection-related hemolysis and susceptibility to Gram-negative bacterial co-infection.

Authors:  Katharine Orf; Aubrey J Cunnington
Journal:  Front Microbiol       Date:  2015-06-30       Impact factor: 5.640

6.  The importance of pathogen load.

Authors:  Aubrey J Cunnington
Journal:  PLoS Pathog       Date:  2015-01-08       Impact factor: 6.823

7.  Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria.

Authors:  Valerie M Crowley; Kodjo Ayi; Ziyue Lu; Karen T Liby; Michael Sporn; Kevin C Kain
Journal:  Malar J       Date:  2017-11-14       Impact factor: 2.979

8.  Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.

Authors:  Abdirahman Abdi; Lu Yu; David Goulding; Martin K Rono; Philip Bejon; Jyoti Choudhary; Julian Rayner
Journal:  Wellcome Open Res       Date:  2017-11-22

9.  Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria.

Authors:  Hyun Jae Lee; Athina Georgiadou; Michael Walther; Davis Nwakanma; Lindsay B Stewart; Michael Levin; Thomas D Otto; David J Conway; Lachlan J Coin; Aubrey J Cunnington
Journal:  Sci Transl Med       Date:  2018-06-27       Impact factor: 17.956

10.  Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial.

Authors:  Susan M Graham; Junmei Chen; Dominic W Chung; Kevin R Barker; Andrea L Conroy; Michael T Hawkes; Sophie Namasopo; Kevin C Kain; José A López; W Conrad Liles
Journal:  Malar J       Date:  2016-02-02       Impact factor: 2.979

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