Literature DB >> 2422580

A comparative study of modified Bielschowsky, Bodian and thioflavin S stains on Alzheimer's neurofibrillary tangles.

T Yamamoto, A Hirano.   

Abstract

Serial sections of the brains of two cases with Alzheimer's disease were stained with the standard Bodian, modified Bielschowsky (reformed Gros-Schultze's modification) and thioflavin S methods. The numbers of demonstrated Alzheimer's neurofibrillary tangles (NFTs) were different between the two silver stains: from 15 to 75% more NFTs were shown and more distinctly with the modified Bielschowsky stain than with the Bodian stain. Many of the NFTs in both cases were of eosinophilic and less argentophilic type. Although the NFTs were not counted, the thioflavin S stain seemed to have no apparent advantage over the modified Bielschowsky stain in the demonstration of NFTs.

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Year:  1986        PMID: 2422580     DOI: 10.1111/j.1365-2990.1986.tb00677.x

Source DB:  PubMed          Journal:  Neuropathol Appl Neurobiol        ISSN: 0305-1846            Impact factor:   8.090


  100 in total

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