Literature DB >> 24225561

Probing kojic acid binding to tyrosinase enzyme: insights from a model complex and QM/MM calculations.

Constance Bochot1, Aurélie Gouron, Luigi Bubacco, Anne Milet, Christian Philouze, Marius Réglier, Guy Serratrice, Hélène Jamet, Catherine Belle.   

Abstract

An unambiguous picture of the interaction between the inhibitor kojic acid and a model of the dicopper active site of tyrosinase is reported. The observed binding mode probed on bacterial enzyme is confirmed and further refined by QM/MM calculations.

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Year:  2013        PMID： 24225561     DOI： 10.1039/c3cc47469k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Human tyrosinase produced in insect cells: a landmark for the screening of new drugs addressing its activity.

Authors:  Stefano Fogal; Marcello Carotti; Laura Giaretta; Federico Lanciai; Leonardo Nogara; Luigi Bubacco; Elisabetta Bergantino
Journal:  Mol Biotechnol       Date:  2015-01       Impact factor: 2.695

2.  The unravelling of the complex pattern of tyrosinase inhibition.

Authors:  Batel Deri; Margarita Kanteev; Mor Goldfeder; Daniel Lecina; Victor Guallar; Noam Adir; Ayelet Fishman
Journal:  Sci Rep       Date:  2016-10-11       Impact factor: 4.379

3.  Evaluating the Performance of a Non-Bonded Cu2+ Model Including Jahn-Teller Effect into the Binding of Tyrosinase Inhibitors.

Authors:  Lucas Sousa Martins; Jerônimo Lameira; Hendrik G Kruger; Cláudio Nahum Alves; José Rogério A Silva
Journal:  Int J Mol Sci       Date:  2020-07-06       Impact factor: 5.923

4.  Catalytic mechanism of the tyrosinase reaction toward the Tyr98 residue in the caddie protein.

Authors:  Yasuyuki Matoba; Shogo Kihara; Naohiko Bando; Hironari Yoshitsu; Miyuki Sakaguchi; Kure'e Kayama; Sachiko Yanagisawa; Takashi Ogura; Masanori Sugiyama
Journal:  PLoS Biol       Date:  2018-12-31       Impact factor: 8.029
  4 in total

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