Literature DB >> 24224687

Patients' and physicians' perspectives on opioid therapy for chronic cancer and musculoskeletal pain in Germany, Italy, and Turkey: PAin RESearch (PARES) survey.

Gerhard H H Müller-Schwefe1, Antonie M Wimmer, Joachim Dejonckheere, Antje Eggers, Renato Vellucci.   

Abstract

OBJECTIVE: Under-treatment or lack of appropriate treatment for chronic pain remains an ongoing major healthcare problem. Opioids are being increasingly recognized as an effective option for chronic pain management. The objective of this survey was to understand the perspective of patients treated with opioids on quality of treatment, preferences, and possibilities to improve treatment and communication between patients and physicians. RESEARCH
DESIGN: A large-scale PAin RESearch (PARES) survey of 2860 patients (Germany, Italy, and Turkey) with chronic cancer or musculoskeletal pain prescribed opioid therapy was conducted to assess various factors such as ease of use and compliance, sleep, quality-of-life, and polymedication. A physician component was also included. Relationships between variables and differences between groups were tested using Spearman and Wilcoxon signed-rank tests, respectively.
RESULTS: Of the patients surveyed, 61% received strong opioids (WHO III) and 39% weak opioids (WHO II). Nearly 65% of the patients were currently on a twice daily or more dosing schedule; however, 61.5% of the patients responded that they considered once-daily dosing to be the most convenient schedule. Patients' responses indicated that different dosing schedules significantly influenced the occurrence of end-of-dose pain, feeling limited by the remaining level of pain, problems in falling asleep, and episodes of waking up at night or early in the morning. Physicians' responses showed that they were not surprised by 68.5% of patient responses; they also felt the need to change some aspect of pain treatment for a third of the patients, the commonest being pain medication (52.4%).
CONCLUSIONS: The results of the survey suggest that patients prefer a convenient dosing scheme, which may have a positive impact on compliance. Physicians may have to communicate more closely with patients about their needs.

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Year:  2013        PMID: 24224687     DOI: 10.1185/03007995.2013.861349

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  5 in total

Review 1.  Spinal Cord Stimulation to Treat Unresponsive Cancer Pain: A Possible Solution in Palliative Oncological Therapy.

Authors:  Federica Paolini; Gianluca Ferini; Lapo Bonosi; Roberta Costanzo; Lara Brunasso; Umberto Emanuele Benigno; Massimiliano Porzio; Rosa Maria Gerardi; Giuseppe Roberto Giammalva; Giuseppe Emmanuele Umana; Francesca Graziano; Gianluca Scalia; Carmelo Lucio Sturiale; Rina Di Bonaventura; Domenico Gerardo Iacopino; Rosario Maugeri
Journal:  Life (Basel)       Date:  2022-04-07

Review 2.  Progress in palliative care for cancer in Turkey: a review of the literature.

Authors:  Tezer Kutluk; Fahad Ahmed; Mustafa Cemaloğlu; Burça Aydın; Meltem Şengelen; Meral Kirazli; Sema Yurduşen; Richard Sullivan; Richard Harding
Journal:  Ecancermedicalscience       Date:  2021-11-25

3.  Bioavailability of oxycodone after administration of a new prolonged-release once-daily tablet formulation in healthy subjects, in comparison to an established twice-daily tablet
.

Authors:  Bernhard Scheidel; Martina A Maritz; Yves J Gschwind; Kerstin Steigerwald; Volker Guth; Peter Kovacs; Helene Rey
Journal:  Int J Clin Pharmacol Ther       Date:  2017-11       Impact factor: 1.366

4.  Once-Daily Oxycodone Prolonged-Release Tablets Are Resistant to Alcohol-Induced Dose Dumping: Results From a Randomized Trial in Healthy Volunteers.

Authors:  Nils Burger; Douglas Fraser; Martina Alice Maritz; Janice Faulkner; Helene Rey
Journal:  Clin Transl Sci       Date:  2020-02-07       Impact factor: 4.689

5.  Questionnaire-Based Survey during COVID-19 Vaccination on the Prevalence of Elderly's Migraine, Chronic Daily Headache, and Medication-Overuse Headache in One Japanese City-Itoigawa Hisui Study.

Authors:  Masahito Katsuki; Junko Kawahara; Yasuhiko Matsumori; Chinami Yamagishi; Akihito Koh; Shin Kawamura; Kenta Kashiwagi; Tomohiro Kito; Akio Entani; Toshiko Yamamoto; Miyako Otake; Takashi Ikeda; Fuminori Yamagishi
Journal:  J Clin Med       Date:  2022-08-11       Impact factor: 4.964

  5 in total

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