New α-Tetralone Galloylglucosides from the Fresh Pericarps of Juglans sigillata.

Three new α-tetralone galloylglucosides (1-3), were isolated from the fresh pericarps of Juglans sigillata (Juglandaceae), together with the six known ones. The structures of the new compounds were determined as 4,6-dihydroxy-α-tetralone-4-O-[6'-O-(3″, 4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (1), (4S)-4,5-dihydroxy-α-tetralone-4-O-[6'-O-(3″,4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (2) and (4S)-4,5,6-tri-hydroxy-α-tetralone-4-O-[6'-O-(3″,4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (3), respectively, on the basis of detailed spectroscopic analyses, and acidic and enzymatic hydrolysis. The antimicrobial activities of the isolated compounds (2, 4 and 7-9) were evaluated.