| Literature DB >> 24222466 |
Tyler D Scherr1, Kevin E Lindgren, Carolyn R Schaeffer, Mark L Hanke, Curtis W Hartman, Tammy Kielian.
Abstract
Animal models are invaluable tools for translational research, allowing investigators to recapitulate observed clinical scenarios within the laboratory that share attributes with human disease. Here, we describe a mouse model of post-arthroplasty Staphylococcus epidermidis joint infection which mimics human disease and may be utilized to explore the complex series of events during staphylococcal implant-associated infections by identifying key immunological, bacterial, and/or therapeutic mechanisms relevant to these persistent infections.Entities:
Mesh：
Year: 2014 PMID： 24222466 DOI： 10.1007/978-1-62703-736-5_16
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745