| Literature DB >> 24222457 |
Abstract
Phenol-soluble modulins (PSMs) are multifunctional peptide toxins produced by many staphylococcal strains. PSMs have received much recent attention, owing to multiple reports underscoring their importance for staphylococcal pathogenesis. Members of the PSM family may be strongly cytolytic to neutrophils and other cell types; promote inflammatory, receptor-mediated responses in several human cell types; and contribute to biofilm structuring and detachment. Here we describe biochemical methods to isolate, purify, and quantitatively analyze Staphylococcus epidermidis PSMs.Entities:
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Year: 2014 PMID： 24222457 DOI： 10.1007/978-1-62703-736-5_7
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745