Literature DB >> 24222075

Analysis of coumarins by micro high-performance liquid chromatography-mass spectrometry with a particle beam interface.

A Cappiello1, G Famiglini, F Mangani, B Tirillini.   

Abstract

Coumarins are a large group of compounds that are naturally present in plant tissues and that exhibit a wide range of pharmacological properties. Analytical methods based on chromatographic techniques and conventional detectors are inadequate to accurately analyze coumarins in complex matrices such as plant extracts. In this article a new method based on a modified particle beam liquid chromatography-mass spectrometry interface is described. The method allows specific and accurate determination of several coumarins in biological matrices. An application regarding the analysis of 18 coumarins in the extract of Smyrnium perfoliatum L. is also reported.

Entities:  

Year:  1995        PMID: 24222075     DOI: 10.1016/S1044-0305(94)00096-I

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN: 1044-0305            Impact factor:   3.109


  4 in total

1.  Use of particle beam liquid chromatography-electron impact mass spectrometry for structure elucidation of oxodipine and three of its metabolites.

Authors:  C Julien-Larose; P Voirin; C Mas-Chamberlin; A Dufour
Journal:  J Chromatogr       Date:  1991-01-02

2.  Gas chromatographic-mass spectrometric analysis of monodemethylated metabolites of 6,7- and 7,8-dimethoxycoumarin isomers.

Authors:  K Yamamoto; S Kato; H Shimomura
Journal:  J Chromatogr       Date:  1986-07-18

3.  Constituents of Justicia pectoralis Jacq. 2. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives.

Authors:  J X de Vries; B Tauscher; G Wurzel
Journal:  Biomed Environ Mass Spectrom       Date:  1988-04-15

4.  Simultaneous determination of beclomethasone, beclomethasone monopropionate and beclomethasone dipropionate in biological fluids using a particle beam interface for combining liquid chromatography with negative-ion chemical ionization mass spectrometry.

Authors:  J Girault; B Istin; J M Malgouyat; A M Brisson; J B Fourtillan
Journal:  J Chromatogr       Date:  1991-03-08
  4 in total

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