Massimo Del Fabbro1,2,3, Stefano Corbella1,2, Valentina Ceresoli1,2, Caterina Ceci1,2, Silvio Taschieri1,2,4. 1. Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy. 2. Dental Clinic, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy. 3. Università degli Studi di Milano, Milan, Italy. 4. Research Center in Oral Health, Università degli Studi di Milano, Milan, Italy.
Abstract
PURPOSE: The control of postoperative discomfort may improve the patient's quality of life as well as treatment acceptance. The aim of the present preliminary report was to assess if the use of autologous platelet concentrate during maxillary sinus augmentation may have a favorable impact on pain and other factors related to patient's quality of life in the first week after surgery. MATERIALS AND METHODS: This is an interim report of a randomized single-blind study. Fifteen patients with atrophic edentulous posterior maxilla underwentmaxillary sinus augmentation using deproteinized bovine bone matrix (DBBM) as the grafting material (control group). In other 15 patients (test group), autologous plasma rich in growth factors (P-PRP) was added to DBBM, then a P-PRP clot was applied to covering the graft before suturing and finally P-PRP was placed over the suture in liquid form. During the first week postsurgery, all patients filled in a questionnaire for evaluation of main symptoms and daily activities. The outcomes of the questionnaires of the two groups were statistically compared. RESULTS: In the first days postsurgery, the group using P-PRP reported significantly less pain, swelling, and hematoma, and improved functional activities with respect to the control group. CONCLUSIONS: The adjunct of P-PRP to the maxillary sinus augmentation procedure produced a beneficial effect to patients' quality of life in the early postsurgical phase.
RCT Entities:
PURPOSE: The control of postoperative discomfort may improve the patient's quality of life as well as treatment acceptance. The aim of the present preliminary report was to assess if the use of autologous platelet concentrate during maxillary sinus augmentation may have a favorable impact on pain and other factors related to patient's quality of life in the first week after surgery. MATERIALS AND METHODS: This is an interim report of a randomized single-blind study. Fifteen patients with atrophic edentulous posterior maxilla underwent maxillary sinus augmentation using deproteinized bovine bone matrix (DBBM) as the grafting material (control group). In other 15 patients (test group), autologous plasma rich in growth factors (P-PRP) was added to DBBM, then a P-PRP clot was applied to covering the graft before suturing and finally P-PRP was placed over the suture in liquid form. During the first week postsurgery, all patients filled in a questionnaire for evaluation of main symptoms and daily activities. The outcomes of the questionnaires of the two groups were statistically compared. RESULTS: In the first days postsurgery, the group using P-PRP reported significantly less pain, swelling, and hematoma, and improved functional activities with respect to the control group. CONCLUSIONS: The adjunct of P-PRP to the maxillary sinus augmentation procedure produced a beneficial effect to patients' quality of life in the early postsurgical phase.
Authors: Aleshba S Khan; Naauman Zaheer; Abdul M Zaigham; Maliha Shahbaz; Usman Zaheer; Mohammad Khursheed Alam Journal: Biomed Res Int Date: 2021-03-13 Impact factor: 3.411
Authors: Carlo Rengo; Antonino Fiorino; Alessandro Cucchi; Antonio Nappo; Emanuele Randellini; Paolo Calamai; Marco Ferrari Journal: Clin Oral Investig Date: 2021-02-23 Impact factor: 3.573
Authors: Ana Cristina Escudero-Escudero; Antonio Segura-Fragoso; Pablo A Cantero-Garlito Journal: Int J Environ Res Public Health Date: 2020-05-02 Impact factor: 3.390