| Literature DB >> 24218277 |
Markryan Dwyer1, Mihaela Gadjeva.
Abstract
The opsonophagocytic killing (OPK) assay is used as a correlate for protection to measure the functional capacities of vaccine-candidate-raised antibodies. This in vitro assay aids selecting promising vaccines by demonstrating whether the vaccine-induced antibodies drive efficient complement deposition and subsequent opsonophagocytic killing. Here, we describe two protocols for an OPK assay using either human-derived PMNs or cultured HL-60 cells.Entities:
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Year: 2014 PMID： 24218277 DOI： 10.1007/978-1-62703-724-2_32
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745