Literature DB >> 2421762

Amino acid sequence of bovine brain derived class 1 heparin-binding growth factor.

D J Strydom, J W Harper, R R Lobb.   

Abstract

The major class 1 heparin-binding growth factor from bovine brain is a single-chain polypeptide of 140 amino acids with a molecular weight of 15 877. It has the amino acid sequence Phe1-Asn-Leu-Pro-Leu-Gly-Asn-Tyr-Lys-Lys-Pro-Lys-Leu-Leu- Tyr15-Cys-Ser- Asn-Gly-Gly-Tyr-Phe-Leu-Arg-Ile-Leu-Pro-Asp-Gly-Thr30-Val-Asp-Gly- Thr-Lys-Asp-Arg- Ser-Asp-Gln-His-Ile-Gln-Leu-Gln45-Leu-Cys-Ala-Glu-Ser-Ile-Gly- Glu-Val-Tyr-Ile- Lys-Ser-Thr-Glu60-Thr-Gly-Gln-Phe-Leu-Ala-Met-Asp-Thr-Asp-Gly- Leu-Leu-Tyr-Gly75- Ser-Gln-Thr-Pro-Asn-Glu-Glu-Cys-Leu-Phe-Leu-Glu-Arg-Leu- Glu90-Glu-Asn-His-Tyr- Asn-Thr-Tyr-Ile-Ser-Lys-Lys-His-Ala-Glu-Lys105-His-Trp-Phe-Val -Gly-Leu-Lys-Lys- Asn-Gly-Arg-Ser-Lys-Leu-Gly120-Pro-Arg-Thr-His-Phe-Gly-Gln-Lys -Ala-Ile-Leu-Phe-Leu-Pro-Leu135-Pro-Val-Ser-Ser-Asp140-OH. The mitogen is homologous to the class 2 heparin-binding growth factor pituitary fibroblast growth factor with about 50% of the amino acids being identical between the two mitogens.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 2421762     DOI： 10.1021/bi00353a001

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  7 in total

1.  Mesoderm-inducing factors. Their possible relationship to heparin-binding growth factors and transforming growth factor-beta.

Authors:  W Knöchel; J Born; P Hoppe; B Loppnow-Blinde; H Tiedemann; H Tiedemann; W L McKeehan; H Grunz
Journal:  Naturwissenschaften       Date:  1987-12

2.  Human recombinant insulin-like growth factor I. I. Development of a serum-free medium for clonal density assay of growth factors using BALB/c 3T3 mouse embryo fibroblasts.

Authors:  T L Riss; K P Karey; B D Burleigh; D Parker; D A Sirbasku
Journal:  In Vitro Cell Dev Biol       Date:  1988-11

3.  Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells.

Authors:  Yang Zhou; Linzhu Ren; Jianguo Zhu; Sen Yan; Haijun Wang; Na Song; Li Li; Hongsheng Ouyang; Daxin Pang
Journal:  Mol Cell Biochem       Date:  2011-04-03       Impact factor: 3.396

4.  Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme.

Authors:  M R Ehlers; E A Fox; D J Strydom; J F Riordan
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

5.  Heparin-binding growth factor type one and platelet-derived growth factor are required for the optimal expression of cell surface low density lipoprotein receptor binding activity in human adult arterial smooth muscle cells.

Authors:  J K Chen; H Hoshi; W L McKeehan
Journal:  In Vitro Cell Dev Biol       Date:  1988-03

6.  Comparative endocrinology-paracrinology-autocrinology of human adult large vessel endothelial and smooth muscle cells.

Authors:  H Hoshi; M Kan; J K Chen; W L Mckeehan
Journal:  In Vitro Cell Dev Biol       Date:  1988-04

7.  Inhibition of endothelial cell proliferation by gamma-interferon.

Authors:  R Friesel; A Komoriya; T Maciag
Journal:  J Cell Biol       Date:  1987-03       Impact factor: 10.539
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.