Literature DB >> 24217159

Beyond anti-PCSK9 therapies: the potential role of resistin inhibitors.

Amirhossein Sahebkar1.   

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Year:  2013        PMID: 24217159     DOI: 10.1038/nrcardio.2013.139-c1

Source DB:  PubMed          Journal:  Nat Rev Cardiol        ISSN: 1759-5002            Impact factor:   32.419


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  9 in total

1.  Dyslipidaemia: PCSK9 antibodies: a dividend of the genomics revolution.

Authors:  Michael H Davidson
Journal:  Nat Rev Cardiol       Date:  2013-09-10       Impact factor: 32.419

2.  The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.

Authors:  Eric N Hampton; Mark W Knuth; Jun Li; Jennifer L Harris; Scott A Lesley; Glen Spraggon
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-05       Impact factor: 11.205

3.  Effect of a monoclonal antibody to PCSK9 on LDL cholesterol.

Authors:  Evan A Stein; Scott Mellis; George D Yancopoulos; Neil Stahl; Douglas Logan; William B Smith; Eleanor Lisbon; Maria Gutierrez; Cheryle Webb; Richard Wu; Yunling Du; Therese Kranz; Evelyn Gasparino; Gary D Swergold
Journal:  N Engl J Med       Date:  2012-03-22       Impact factor: 91.245

4.  Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/kexin type 9.

Authors:  Michelle Melone; Larissa Wilsie; Oksana Palyha; Alison Strack; Shirya Rashid
Journal:  J Am Coll Cardiol       Date:  2012-05-08       Impact factor: 24.094

5.  Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy.

Authors:  James M McKenney; Michael J Koren; Dean J Kereiakes; Corinne Hanotin; Anne-Catherine Ferrand; Evan A Stein
Journal:  J Am Coll Cardiol       Date:  2012-03-28       Impact factor: 24.094

Review 6.  Resistin: functional roles and therapeutic considerations for cardiovascular disease.

Authors:  Md S Jamaluddin; Sarah M Weakley; Qizhi Yao; Changyi Chen
Journal:  Br J Pharmacol       Date:  2012-02       Impact factor: 8.739

7.  Low-density lipoprotein cholesterol-lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypercholesterolemia: the Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD) randomized trial.

Authors:  Frederick Raal; Rob Scott; Ransi Somaratne; Ian Bridges; Gang Li; Scott M Wasserman; Evan A Stein
Journal:  Circulation       Date:  2012-11-05       Impact factor: 29.690

8.  Effect of a monoclonal antibody to PCSK9 on low-density lipoprotein cholesterol levels in statin-intolerant patients: the GAUSS randomized trial.

Authors:  David Sullivan; Anders G Olsson; Rob Scott; Jae B Kim; Allen Xue; Val Gebski; Scott M Wasserman; Evan A Stein
Journal:  JAMA       Date:  2012-12-19       Impact factor: 56.272

9.  Atorvastatin with or without an antibody to PCSK9 in primary hypercholesterolemia.

Authors:  Eli M Roth; James M McKenney; Corinne Hanotin; Gaelle Asset; Evan A Stein
Journal:  N Engl J Med       Date:  2012-10-31       Impact factor: 91.245

  9 in total
  3 in total

Review 1.  Vision from next generation sequencing: multi-dimensional genome-wide analysis for producing gene regulatory networks underlying retinal development, aging and disease.

Authors:  Hyun-Jin Yang; Rinki Ratnapriya; Tiziana Cogliati; Jung-Woong Kim; Anand Swaroop
Journal:  Prog Retin Eye Res       Date:  2015-02-07       Impact factor: 21.198

2.  Diabetic cardiomyopathy: is resistin a culprit?

Authors:  Djamel Lebeche
Journal:  Cardiovasc Diagn Ther       Date:  2015-10

3.  The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research.

Authors:  Ahmed Elguindy; Magdi H Yacoub
Journal:  Glob Cardiol Sci Pract       Date:  2013-12-30
  3 in total

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