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Literature DB >> 24216389

The gut microbiome as novel cardio-metabolic target: the time has come!

Sarah Vinjé¹, Erik Stroes, Max Nieuwdorp, Stan L Hazen.

Abstract

Recent studies reveal a potential contribution of intestinal microbes in the expression of certain human cardio-metabolic diseases. The mechanisms through which intestinal microbiota and/or their metabolic products alter systemic homoeostasis and cardio-metabolic disease risks are just beginning to be dissected. Intervention studies in humans aiming to either selectively alter the composition of the intestinal microbiota or to pharmacologically manipulate the microbiota to influence production of their metabolites are crucial next steps. The intestinal microbiome represents a new potential therapeutic target for the treatment of cardio-metabolic diseases.

Entities: Disease Species

Keywords: Atherothrombosis; Gutmicrobiota; Insulin resistance; Obesity; TMAO; Therapy; Vascular inflammation

Mesh：

Year: 2013 PMID： 24216389 PMCID： PMC3977135 DOI： 10.1093/eurheartj/eht467

Source DB: PubMed Journal: Eur Heart J ISSN： 0195-668X Impact factor: 29.983

58 in total

1. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study.

Authors: Susanne Mueller; Katiana Saunier; Christiana Hanisch; Elisabeth Norin; Livia Alm; Tore Midtvedt; Alberto Cresci; Stefania Silvi; Carla Orpianesi; Maria Cristina Verdenelli; Thomas Clavel; Corinna Koebnick; Hans-Joachim Franz Zunft; Joël Doré; Michael Blaut
Journal: Appl Environ Microbiol Date: 2006-02 Impact factor: 4.792

Review 2. Role of flagellin in Crohn's disease: emblematic of the progress and enigmas in understanding inflammatory bowel disease.

Authors: Matam Vijay-Kumar; Andrew T Gewirtz
Journal: Inflamm Bowel Dis Date: 2009-05 Impact factor: 5.325

3. Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.

Authors: Myung H Kim; Seung G Kang; Jeong H Park; Masashi Yanagisawa; Chang H Kim
Journal: Gastroenterology Date: 2013-05-07 Impact factor: 22.682

4. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice.

Authors: Fredrik Bäckhed; Jill K Manchester; Clay F Semenkovich; Jeffrey I Gordon
Journal: Proc Natl Acad Sci U S A Date: 2007-01-08 Impact factor: 11.205

5. A metagenome-wide association study of gut microbiota in type 2 diabetes.

Authors: Junjie Qin; Yingrui Li; Zhiming Cai; Shenghui Li; Jianfeng Zhu; Fan Zhang; Suisha Liang; Wenwei Zhang; Yuanlin Guan; Dongqian Shen; Yangqing Peng; Dongya Zhang; Zhuye Jie; Wenxian Wu; Youwen Qin; Wenbin Xue; Junhua Li; Lingchuan Han; Donghui Lu; Peixian Wu; Yali Dai; Xiaojuan Sun; Zesong Li; Aifa Tang; Shilong Zhong; Xiaoping Li; Weineng Chen; Ran Xu; Mingbang Wang; Qiang Feng; Meihua Gong; Jing Yu; Yanyan Zhang; Ming Zhang; Torben Hansen; Gaston Sanchez; Jeroen Raes; Gwen Falony; Shujiro Okuda; Mathieu Almeida; Emmanuelle LeChatelier; Pierre Renault; Nicolas Pons; Jean-Michel Batto; Zhaoxi Zhang; Hua Chen; Ruifu Yang; Weimou Zheng; Songgang Li; Huanming Yang; Jian Wang; S Dusko Ehrlich; Rasmus Nielsen; Oluf Pedersen; Karsten Kristiansen; Jun Wang
Journal: Nature Date: 2012-09-26 Impact factor: 49.962

6. Detection of periodontal bacteria in atheromatous plaque by nested polymerase chain reaction.

Authors: Elena Figuero; María Sánchez-Beltrán; Susana Cuesta-Frechoso; Jose María Tejerina; Jose Antonio del Castro; Jose María Gutiérrez; David Herrera; Mariano Sanz
Journal: J Periodontol Date: 2011-03-29 Impact factor: 6.993

7. Parenteral nutrition facilitates activation of coagulation but not of fibrinolysis during human endotoxemia.

Authors: T van der Poll; M Levi; C C Braxton; S M Coyle; M Roth; J W ten Cate; S F Lowry
Journal: J Infect Dis Date: 1998-03 Impact factor: 5.226

8. The gut microbiota as an environmental factor that regulates fat storage.

Authors: Fredrik Bäckhed; Hao Ding; Ting Wang; Lora V Hooper; Gou Young Koh; Andras Nagy; Clay F Semenkovich; Jeffrey I Gordon
Journal: Proc Natl Acad Sci U S A Date: 2004-10-25 Impact factor: 11.205

9. Red meat consumption and mortality: results from 2 prospective cohort studies.

Authors: An Pan; Qi Sun; Adam M Bernstein; Matthias B Schulze; JoAnn E Manson; Meir J Stampfer; Walter C Willett; Frank B Hu
Journal: Arch Intern Med Date: 2012-03-12

10. Linking long-term dietary patterns with gut microbial enterotypes.

Authors: Gary D Wu; Jun Chen; Christian Hoffmann; Kyle Bittinger; Ying-Yu Chen; Sue A Keilbaugh; Meenakshi Bewtra; Dan Knights; William A Walters; Rob Knight; Rohini Sinha; Erin Gilroy; Kernika Gupta; Robert Baldassano; Lisa Nessel; Hongzhe Li; Frederic D Bushman; James D Lewis
Journal: Science Date: 2011-09-01 Impact factor: 47.728

30 in total

Review 1. Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health.

Authors: Carl D Koch; Mark T Gladwin; Bruce A Freeman; Jon O Lundberg; Eddie Weitzberg; Alison Morris
Journal: Free Radic Biol Med Date: 2016-12-16 Impact factor: 7.376

2. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction.

Authors: Krishna M Boini; Tahir Hussain; Pin-Lan Li; Sai Koka
Journal: Cell Physiol Biochem Date: 2017-11-06

Review 3. Circadian regulation of metabolism.

Authors: Shannon M Bailey; Uduak S Udoh; Martin E Young
Journal: J Endocrinol Date: 2014-06-13 Impact factor: 4.286

4. Gallstones and Risk of Coronary Heart Disease: Prospective Analysis of 270 000 Men and Women From 3 US Cohorts and Meta-Analysis.

Authors: Yan Zheng; Min Xu; Yanping Li; Adela Hruby; Eric B Rimm; Frank B Hu; Janine Wirth; Christine M Albert; Kathryn M Rexrode; JoAnn E Manson; Lu Qi
Journal: Arterioscler Thromb Vasc Biol Date: 2016-08-18 Impact factor: 8.311

5. SMV1, an extremely stable thermophilic virus platform for nanoparticle trafficking in the mammalian GI tract.

Authors: K B Uldahl; S T Walk; S C Olshefsky; M J Young; X Peng
Journal: J Appl Microbiol Date: 2017-10-10 Impact factor: 3.772

Review 6. Systemic impact of intestinal helminth infections.

Authors: P K Mishra; M Palma; D Bleich; P Loke; W C Gause
Journal: Mucosal Immunol Date: 2014-04-16 Impact factor: 7.313

Review 7. Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease.

Authors: Jianhua Zhang; Matilda Lillian Culp; Jason G Craver; Victor Darley-Usmar
Journal: J Neurochem Date: 2018-02-14 Impact factor: 5.372

Review 8. The Use of Fecal Microbiome Transplant in Treating Human Diseases: Too Early for Poop?

Authors: Hooi-Leng Ser; Vengadesh Letchumanan; Bey-Hing Goh; Sunny Hei Wong; Learn-Han Lee
Journal: Front Microbiol Date: 2021-05-13 Impact factor: 5.640

Review 9. Sex differences in the intestinal microbiome: interactions with risk factors for atherosclerosis and cardiovascular disease.

Authors: Shamon Ahmed; J David Spence
Journal: Biol Sex Differ Date: 2021-05-17 Impact factor: 5.027

Review 10. Gut microbiota in renal physiology: focus on short-chain fatty acids and their receptors.

Authors: Jennifer L Pluznick
Journal: Kidney Int Date: 2016-08-26 Impact factor: 10.612