Literature DB >> 24215409

Accelerated telomere shortening in rheumatic diseases: cause or consequence?

Amina Z A Dehbi1, Timothy R D J Radstake, Jasper C A Broen.   

Abstract

Accelerated aging of the immune system (immune aging), represented by telomere shortening, has been implicated in a variety of rheumatic diseases. Studies addressing telomere shortening in rheumatic diseases so far yielded controversial results. The current review aims to provide an overview on the role of immune aging in a plethora of immune-mediated conditions including systemic sclerosis, rheumatoid arthritis, systemic lupus erythematosus and osteoarthritis. The main question this review aims to answer is whether rheumatic diseases cause accelerated aging or that accelerated aging drives rheumatic diseases.

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Year:  2013        PMID： 24215409     DOI： 10.1586/1744666X.2013.850031

Source DB:  PubMed          Journal:  Expert Rev Clin Immunol        ISSN： 1744-666X            Impact factor:   4.473


  8 in total

1.  Association between shortened telomere length and rheumatoid arthritis : A meta-analysis.

Authors:  Y H Lee; S-C Bae
Journal:  Z Rheumatol       Date:  2018-03       Impact factor: 1.372

Review 2.  Aging of the Immune System. Mechanisms and Therapeutic Targets.

Authors:  Cornelia M Weyand; Jörg J Goronzy
Journal:  Ann Am Thorac Soc       Date:  2016-12

3.  Telomere dysfunction-related serological markers and oxidative stress markers in rheumatoid arthritis patients: correlation with diseases activity.

Authors:  Rania M Gamal; Nevin Hammam; Madeha M Zakary; Marwa Mahmoud Abdelaziz; Mohamed Raouf Abdel Razek; Mona Sallam Embarek Mohamed; Yaser Emad; Mohamed Galal Elnaggar; Daniel E Furst
Journal:  Clin Rheumatol       Date:  2018-10-16       Impact factor: 2.980

Review 4.  Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis.

Authors:  Sonsoles Piera-Velazquez; Sergio A Jimenez
Journal:  Curr Rheumatol Rep       Date:  2015-01       Impact factor: 4.592

5.  Social Factors, Epigenomics and Lupus in African American Women (SELA) Study: protocol for an observational mechanistic study examining the interplay of multiple individual and social factors on lupus outcomes in a health disparity population.

Authors:  Emily L Vara; Carl D Langefeld; Bethany J Wolf; Timothy D Howard; Gregory A Hawkins; Queen Quet; Lee H Moultrie; L Quinnette King; Ivan D Molano; Stephanie L Bray; Lori Ann Ueberroth; S Sam Lim; Edith M Williams; Diane L Kamen; Paula S Ramos
Journal:  Lupus Sci Med       Date:  2022-06

Review 6.  The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?

Authors:  Vasileios Kordinas; Anastasios Ioannidis; Stylianos Chatzipanagiotou
Journal:  Genes (Basel)       Date:  2016-09-03       Impact factor: 4.096

7.  Aberrant leukocyte telomere length in Birdshot Uveitis.

Authors:  Nadia Vazirpanah; Fleurieke H Verhagen; Anna Rothova; Tom O A R Missotten; Mirjam van Velthoven; Anneke I Den Hollander; Carel B Hoyng; Timothy R D J Radstake; Jasper C A Broen; Jonas J W Kuiper
Journal:  PLoS One       Date:  2017-05-01       Impact factor: 3.240

Review 8.  Molecular Basis of Accelerated Aging with Immune Dysfunction-Mediated Inflammation (Inflamm-Aging) in Patients with Systemic Sclerosis.

Authors:  Chieh-Yu Shen; Cheng-Hsun Lu; Cheng-Han Wu; Ko-Jen Li; Yu-Min Kuo; Song-Chou Hsieh; Chia-Li Yu
Journal:  Cells       Date:  2021-12-02       Impact factor: 6.600
  8 in total

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