Literature DB >> 24212674

Independent hypothalamic circuits for social and predator fear.

Bianca A Silva1, Camilla Mattucci, Piotr Krzywkowski, Emanuele Murana, Anna Illarionova, Valery Grinevich, Newton S Canteras, Davide Ragozzino, Cornelius T Gross.   

Abstract

The neural circuits mediating fear to naturalistic threats are poorly understood. We found that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), a region that has been implicated in feeding, sex and aggression, are essential for predator and social fear in mice. Our results establish a critical role for VMH in fear and have implications for selective intervention in pathological fear in humans.

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Year:  2013        PMID： 24212674      PMCID： PMC4194278          DOI： 10.1038/nn.3573

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  20 in total

Review 1.  The medial hypothalamic defensive system: hodological organization and functional implications.

Authors:  Newton S Canteras
Journal:  Pharmacol Biochem Behav       Date:  2002-03       Impact factor: 3.533

2.  Evoked axonal oxytocin release in the central amygdala attenuates fear response.

Authors:  H Sophie Knobloch; Alexandre Charlet; Lena C Hoffmann; Marina Eliava; Sergey Khrulev; Ali H Cetin; Pavel Osten; Martin K Schwarz; Peter H Seeburg; Ron Stoop; Valery Grinevich
Journal:  Neuron       Date:  2012-02-09       Impact factor: 17.173

3.  The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning.

Authors:  Deborah M Kurrasch; Clement C Cheung; Florence Y Lee; Phu V Tran; Kenji Hata; Holly A Ingraham
Journal:  J Neurosci       Date:  2007-12-12       Impact factor: 6.167

4.  Dissecting the brain's fear system reveals the hypothalamus is critical for responding in subordinate conspecific intruders.

Authors:  Simone C Motta; Marina Goto; Flavia V Gouveia; Marcus V C Baldo; Newton S Canteras; Larry W Swanson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-09       Impact factor: 11.205

5.  Functional identification of an aggression locus in the mouse hypothalamus.

Authors:  Dayu Lin; Maureen P Boyle; Piotr Dollar; Hyosang Lee; E S Lein; Pietro Perona; David J Anderson
Journal:  Nature       Date:  2011-02-10       Impact factor: 49.962

6.  Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.

Authors:  Georgia M Alexander; Sarah C Rogan; Atheir I Abbas; Blaine N Armbruster; Ying Pei; John A Allen; Randal J Nonneman; John Hartmann; Sheryl S Moy; Miguel A Nicolelis; James O McNamara; Bryan L Roth
Journal:  Neuron       Date:  2009-07-16       Impact factor: 17.173

Review 7.  Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain.

Authors:  Richard B Simerly
Journal:  Annu Rev Neurosci       Date:  2002-03-27       Impact factor: 12.449

8.  Induction of panic attack by stimulation of the ventromedial hypothalamus.

Authors:  W Bryan Wilent; Michael Y Oh; Cathrin M Buetefisch; Julian E Bailes; Diane Cantella; Cindy Angle; Donald M Whiting
Journal:  J Neurosurg       Date:  2010-06       Impact factor: 5.115

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Review 10.  Different patterns of freezing behavior organized in the periaqueductal gray of rats: association with different types of anxiety.

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  86 in total

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Journal:  Physiology (Bethesda)       Date:  2015-09

2.  Innate Predator Odor Aversion Driven by Parallel Olfactory Subsystems that Converge in the Ventromedial Hypothalamus.

Authors:  Anabel Pérez-Gómez; Katherin Bleymehl; Benjamin Stein; Martina Pyrski; Lutz Birnbaumer; Steven D Munger; Trese Leinders-Zufall; Frank Zufall; Pablo Chamero
Journal:  Curr Biol       Date:  2015-04-30       Impact factor: 10.834

3.  Skeletal muscle thermogenesis induction by exposure to predator odor.

Authors:  Erin Gorrell; Ashley Shemery; Jesse Kowalski; Miranda Bodziony; Nhlalala Mavundza; Amber R Titus; Mark Yoder; Sarah Mull; Lydia A Heemstra; Jacob G Wagner; Megan Gibson; Olivia Carey; Diamond Daniel; Nicholas Harvey; Meredith Zendlo; Megan Rich; Scott Everett; Chaitanya K Gavini; Tariq I Almundarij; Diane Lorton; Colleen M Novak
Journal:  J Exp Biol       Date:  2020-04-16       Impact factor: 3.312

4.  Social Control of Hypothalamus-Mediated Male Aggression.

Authors:  Taehong Yang; Cindy F Yang; M Delara Chizari; Niru Maheswaranathan; Kenneth J Burke; Maxim Borius; Sayaka Inoue; Michael C Chiang; Kevin J Bender; Surya Ganguli; Nirao M Shah
Journal:  Neuron       Date:  2017-07-27       Impact factor: 17.173

5.  Capturing and Manipulating Activated Neuronal Ensembles with CANE Delineates a Hypothalamic Social-Fear Circuit.

Authors:  Katsuyasu Sakurai; Shengli Zhao; Jun Takatoh; Erica Rodriguez; Jinghao Lu; Andrew D Leavitt; Min Fu; Bao-Xia Han; Fan Wang
Journal:  Neuron       Date:  2016-10-27       Impact factor: 17.173

6.  Periaqueductal Gray Neuronal Activities Underlie Different Aspects of Defensive Behaviors.

Authors:  Hanfei Deng; Xiong Xiao; Zuoren Wang
Journal:  J Neurosci       Date:  2016-07-20       Impact factor: 6.167

7.  Persistent conditioned place preference to aggression experience in adult male sexually-experienced CD-1 mice.

Authors:  S A Golden; H Aleyasin; R Heins; M Flanigan; M Heshmati; A Takahashi; S J Russo; Y Shaham
Journal:  Genes Brain Behav       Date:  2016-08-18       Impact factor: 3.449

8.  Anxiety Cells in a Hippocampal-Hypothalamic Circuit.

Authors:  Jessica C Jimenez; Katy Su; Alexander R Goldberg; Victor M Luna; Jeremy S Biane; Gokhan Ordek; Pengcheng Zhou; Samantha K Ong; Matthew A Wright; Larry Zweifel; Liam Paninski; René Hen; Mazen A Kheirbek
Journal:  Neuron       Date:  2018-01-31       Impact factor: 17.173

9.  Hunger-Driven Motivational State Competition.

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10.  A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.

Authors:  Daniel F Manvich; Taylor A Stowe; Jodi R Godfrey; David Weinshenker
Journal:  Biol Psychiatry       Date:  2015-07-08       Impact factor: 13.382
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