Literature DB >> 24211018

Suggestions for a Web based universal exchange and inference language for medicine.

Barry Robson1, Thomas P Caruso, Ulysses G J Balis.   

Abstract

Mining biomedical and pharmaceutical data generates huge numbers of interacting probabilistic statements for inference, which can be supported by mining Web text sources. This latter can also be probabilistic, in a sense described in this report. However, the diversity of tools for probabilistic inference is troublesome, suggesting a need for a unifying best practice. Physicists often claim that quantum mechanics is the universal best practice for probabilistic reasoning. We discuss how the Dirac notation and algebra suggest the form and algebraic and semantic meaning of XML-like Web tags for a clinical and biomedical universal exchange language formulated to make sense directly to the eye of the physician and biomedical researcher.
© 2013 Published by Elsevier Ltd.

Keywords:  Bayes inference; Best practice; Dirac; Hyperbolic complex algebra; Probabilistic knowledge representation; Semantic networks

Mesh:

Year:  2013        PMID: 24211018     DOI: 10.1016/j.compbiomed.2013.09.010

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN: 0010-4825            Impact factor:   4.589


  5 in total

Review 1.  Towards faster response against emerging epidemics and prediction of variants of concern.

Authors:  B Robson
Journal:  Inform Med Unlocked       Date:  2022-05-20

Review 2.  The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents.

Authors:  Gustavo R Villas-Boas; Vanessa C Rescia; Marina M Paes; Stefânia N Lavorato; Manoel F de Magalhães-Filho; Mila S Cunha; Rafael da C Simões; Roseli B de Lacerda; Renilson S de Freitas-Júnior; Bruno H da S Ramos; Ana M Mapeli; Matheus da S T Henriques; William R de Freitas; Luiz A F Lopes; Luiz G R Oliveira; Jonatas G da Silva; Saulo E Silva-Filho; Ana P S da Silveira; Katyuscya V Leão; Maria M de S Matos; Jamille S Fernandes; Roberto K N Cuman; Francielli M de S Silva-Comar; Jurandir F Comar; Luana do A Brasileiro; Jussileide N Dos Santos; Silvia A Oesterreich
Journal:  Molecules       Date:  2020-09-07       Impact factor: 4.411

Review 3.  COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles' heel conserved region to minimize probability of escape mutations and drug resistance.

Authors:  B Robson
Journal:  Comput Biol Med       Date:  2020-04-11       Impact factor: 4.589

4.  Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans.

Authors:  B Robson
Journal:  Comput Biol Med       Date:  2020-06-08       Impact factor: 4.589

5.  Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-CoV-2 (2019-nCoV, COVID-19) coronavirus.

Authors:  B Robson
Journal:  Comput Biol Med       Date:  2020-02-26       Impact factor: 4.589

  5 in total

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