Literature DB >> 24210837

Relationship of plasma cytokines and clinical biomarkers to memory performance in HIV.

Stephen Correia1, Ronald Cohen, Assawin Gongvatana, Skye Ross, James Olchowski, Kathryn Devlin, Karen Tashima, Bradford Navia, Suzanne Delamonte.   

Abstract

Chronic systemic immune activation and inflammatory processes have been linked to brain dysfunction in medically stable HIV-infected people. We investigated the association between verbal memory performance and plasma concentrations of 13 cytokines measured using multiplexed bead array immunoassay in 74 HIV-seropositive individuals and 50 HIV-seronegative controls. Memory performance was positively related to levels of IL-8 and IFN-γ, and negatively related to IL-10 and IL-18 and to hepatitis C infection. Memory performance was not significantly related to HIV disease markers. The results indicate the importance of systemic immune and inflammatory markers to neurocognitive function in chronic and stable HIV disease.
© 2013.

Entities:  

Keywords:  CART; Cytokines; HIV; HIV clinical markers; Hepatitis C; Memory

Mesh:

Substances:

Year:  2013        PMID: 24210837      PMCID: PMC4422333          DOI: 10.1016/j.jneuroim.2013.09.005

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN: 0165-5728            Impact factor:   3.478


  64 in total

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Journal:  J Immunol       Date:  1997-03-01       Impact factor: 5.422

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Journal:  Zhonghua Yi Xue Za Zhi (Taipei)       Date:  1999-06

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Journal:  Clin Immunol Immunopathol       Date:  1990-11

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Journal:  J Neurovirol       Date:  1997-12       Impact factor: 2.643

Review 6.  Neuropathology of early HIV-1 infection.

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Journal:  Brain Pathol       Date:  1996-01       Impact factor: 6.508

Review 7.  Astrocyte activation and apoptosis: their roles in the neuropathology of HIV infection.

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Journal:  Brain Pathol       Date:  2003-01       Impact factor: 6.508

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Journal:  Nature       Date:  1997-02-13       Impact factor: 49.962

9.  Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.

Authors:  Larisa Poluektova; Santhi Gorantla; Jill Faraci; Kevin Birusingh; Huanyu Dou; Howard E Gendelman
Journal:  J Immunol       Date:  2004-06-15       Impact factor: 5.422

Review 10.  Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

Authors:  G Z Feuerstein; T Liu; F C Barone
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  11 in total

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Journal:  Brain Behav Immun       Date:  2017-01-10       Impact factor: 7.217

2.  Factors related to HIV-associated neurocognitive impairment differ with age.

Authors:  Gary B Fogel; Susanna L Lamers; Andrew J Levine; Miguel Valdes-Sueiras; Michael S McGrath; Paul Shapshak; Elyse J Singer
Journal:  J Neurovirol       Date:  2014-11-18       Impact factor: 2.643

Review 3.  Immune activation and neuroinflammation in alcohol use and HIV infection: evidence for shared mechanisms.

Authors:  Mollie A Monnig
Journal:  Am J Drug Alcohol Abuse       Date:  2016-08-17       Impact factor: 3.829

4.  Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study.

Authors:  Leah H Rubin; Lorie Benning; Sheila M Keating; Philip J Norris; Jane Burke-Miller; Antonia Savarese; Krithika N Kumanan; Saria Awadalla; Gayle Springer; Kathyrn Anastos; Mary Young; Joel Milam; Victor G Valcour; Kathleen M Weber; Pauline M Maki
Journal:  J Neurovirol       Date:  2017-10-23       Impact factor: 2.643

5.  A single low dose of hydrocortisone enhances cognitive functioning in HIV-infected women.

Authors:  Leah H Rubin; K Luan Phan; Sheila M Keating; Pauline M Maki
Journal:  AIDS       Date:  2018-09-10       Impact factor: 4.177

6.  Brief Report: CD14+ Enriched Peripheral Cells Secrete Cytokines Unique to HIV-Associated Neurocognitive Disorders.

Authors:  Melissa A Agsalda-Garcia; Pasiri Sithinamsuwan; Victor G Valcour; Thep Chalermchai; Somporn Tipsuk; Jason Kuroda; Christie Nakamura; Jintanat Ananworanich; Guangxiang Zhang; Alexandra Schuetz; Bonnie M Slike; Bruce Shiramizu
Journal:  J Acquir Immune Defic Syndr       Date:  2017-04-01       Impact factor: 3.731

7.  Remitted depression and cognition in HIV: The role of cortisol and inflammation.

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Journal:  Psychoneuroendocrinology       Date:  2020-02-07       Impact factor: 4.905

8.  The Association of Immune Markers with Cognitive Performance in South African HIV-Positive Patients.

Authors:  Monray E Williams; Jonathan C Ipser; Dan J Stein; John A Joska; Petrus J W Naudé
Journal:  J Neuroimmune Pharmacol       Date:  2019-08-06       Impact factor: 4.147

9.  Peripheral TNFα elevations in abstinent alcoholics are associated with hepatitis C infection.

Authors:  Natalie M Zahr
Journal:  PLoS One       Date:  2018-02-06       Impact factor: 3.240

10.  Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus.

Authors:  Raquel García-García; Álvaro Javier Cruz-Gómez; Amparo Urios; Alba Mangas-Losada; Cristina Forn; Desamparados Escudero-García; Elena Kosenko; Isidro Torregrosa; Joan Tosca; Remedios Giner-Durán; Miguel Angel Serra; César Avila; Vicente Belloch; Vicente Felipo; Carmina Montoliu
Journal:  Sci Rep       Date:  2018-06-25       Impact factor: 4.379

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