M Bouchikh1, A Achir2, M Caidi3, S El Aziz3, A Benosman2. 1. Service de chirurgie thoracique, CHU Ibn-Sina, BP 353, 10001 Rabat, Maroc; Unité de pédagogie et de recherche en chirurgie thoracique, faculté de médecine, Rabat, Maroc. Electronic address: m.bouchikh@um5s.net.ma. 2. Service de chirurgie thoracique, CHU Ibn-Sina, BP 353, 10001 Rabat, Maroc; Unité de pédagogie et de recherche en chirurgie thoracique, faculté de médecine, Rabat, Maroc. 3. Service de chirurgie thoracique, CHU Ibn-Sina, BP 353, 10001 Rabat, Maroc.
Abstract
INTRODUCTION: Multidrug-resistant tuberculosis (MDR-TB) is a worldwide health problem. Surgery is often used as an adjuvent therapy with anti-tuberculosis agents. The aim of this study is to present our results of pulmonary resections in the treatment of MDR-TB. MATERIAL AND METHODS: [corrected] This is a retrospective monocentric study of 29 patients operated on between 1995 and 2010 for MDR-TB. RESULTS: Tuberculosis was evolving from 9 to 108 months with a median of 34.77±19.88 months. The average number of tuberculosis relapses was 2.73 per patient. All patients had a destroyed and/or cavitary parenchyma and 17 had bacilli in sputum at the time of surgery. Lobectomy (51.17%) and pneumonectomy (41.37%) were the main interventions carried out. The operative mortality was 3.44%. Complications such prolonged air leaking and empyema had occurred in 9 patients. The rate of postoperative microbiological conversion was 88.23%. One patient had a relapse 5 months after surgery. CONCLUSION: Surgery associated with medical treatment provides a high cure rate to the detriment of an acceptable morbidity and mortality.
INTRODUCTION: Multidrug-resistant tuberculosis (MDR-TB) is a worldwide health problem. Surgery is often used as an adjuvent therapy with anti-tuberculosis agents. The aim of this study is to present our results of pulmonary resections in the treatment of MDR-TB. MATERIAL AND METHODS: [corrected] This is a retrospective monocentric study of 29 patients operated on between 1995 and 2010 for MDR-TB. RESULTS:Tuberculosis was evolving from 9 to 108 months with a median of 34.77±19.88 months. The average number of tuberculosis relapses was 2.73 per patient. All patients had a destroyed and/or cavitary parenchyma and 17 had bacilli in sputum at the time of surgery. Lobectomy (51.17%) and pneumonectomy (41.37%) were the main interventions carried out. The operative mortality was 3.44%. Complications such prolonged air leaking and empyema had occurred in 9 patients. The rate of postoperative microbiological conversion was 88.23%. One patient had a relapse 5 months after surgery. CONCLUSION: Surgery associated with medical treatment provides a high cure rate to the detriment of an acceptable morbidity and mortality.
Authors: S Shirodkar; L Anande; A Dalal; C Desai; G Corrêa; M Das; C Laxmeshwar; H Mansoor; D Remartinez; M Trelles; P Isaakidis Journal: Public Health Action Date: 2016-09-21