Literature DB >> 24209717

Comparison of frozen and unfrozen blood spots for gene expression studies.

Changshuai Wei1, Qing Lu1, Sok Kean Khoo2, Madeleine Lenski1, Raina N Fichorova3, Alan Leviton4, Nigel Paneth5.   

Abstract

We studied gene expression in 9 sets of paired newborn blood spots stored for 8-10 years in either the frozen state or the unfrozen state. Fewer genes were expressed in unfrozen spots, but the average correlation coefficient for overall gene expression comparing the frozen and unfrozen state was 0.771 (95% CI, 0.700-0.828).
Copyright © 2014 Mosby, Inc. All rights reserved.

Entities:  

Keywords:  ELGAN; Extremely Low Gestational Age Newborns

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Substances:

Year:  2013        PMID: 24209717      PMCID: PMC4326080          DOI: 10.1016/j.jpeds.2013.09.025

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  9 in total

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  7 in total

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