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Literature DB >> 2420832

Lamina propria mast cells in biopsies from children with Crohn's disease.

I R Sanderson, K B Leung, F L Pearce, J A Walker-Smith.

Abstract

Biopsies from actively inflamed areas of terminal ileum or colon in children with Crohn's disease were examined both for lamina propria mast cell density and histamine content. These were reduced in comparison with those of normal controls. The release of histamine from biopsies of inflamed tissue did not differ greatly from that of normal tissue, either spontaneously or after receiving an antihuman IgE challenge.

Entities: Chemical Disease Species

Mesh：

Substances：
Immunoglobulin E

Year: 1986 PMID： 2420832 PMCID： PMC499763 DOI： 10.1136/jcp.39.3.279

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

14 in total

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7. Soluble CD14 is essential for lipopolysaccharide-dependent activation of human intestinal mast cells from macroscopically normal as well as Crohn's disease tissue.

Authors: Sibylle A Brenner; Steffi Zacheja; Michael Schäffer; Katharina Feilhauer; Stephan C Bischoff; Axel Lorentz
Journal: Immunology Date: 2014-10 Impact factor: 7.397