Literature DB >> 24205780

The incidence of vitamin D deficiency amongst patients with a femoral neck fracture: are current bone protection guidelines sufficient ?

David J Bryson1, Jennifer S Nichols, Alan J Ford, Stephen C Williams.   

Abstract

Vitamin D is required for calcium homeostasis and bone metabolism. This prospective observational study examined the incidence of vitamin D deficiency amongst patients with a fracture of the femoral neck, and the correlation between pre-admission use of bone-protection medication and vitamin D levels. Vitamin D assays were available in 75 out of 151 patients admitted with a hip fracture in February-March 2012; the assays were performed within one week of admission and surgery. The incidence of suboptimal vitamin D levels was 90% (68/75), with severe deficiency (<15nmol/l) or deficiency (<30nmol/l) seen in 71% (53/75). Only 7 patients were on bone protection medication at the time of admission, and all of them had suboptimal vitamin D levels. This suggests that the prevention is practically inexistent or at best insufficient. According to the literature, vitamin D deficiency is also associated with falls and maybe with outcome of surgery. Current management strategies may not be sufficient to address vitamin D deficiency and are overlooking an important and potentially modifiable risk factor.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24205780

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  1 in total

1.  Vitamin D insufficiency over 5 years is associated with increased fracture risk-an observational cohort study of elderly women.

Authors:  D Buchebner; F McGuigan; P Gerdhem; J Malm; M Ridderstråle; K Akesson
Journal:  Osteoporos Int       Date:  2014-08-13       Impact factor: 4.507

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.