Literature DB >> 24203529

Captious certainties: makings, meanings and misreadings of consumer-oriented genetic testing.

Norbert W Paul1, Mita Banerjee, Susanne Michl.   

Abstract

Members of the scientific and medical communities concerned with genetic testing might wonder, why cultural and ethical analyses of genetic testing are increasing again, especially since legal frameworks have, by now, come to provide more solid grounds for the routine application of genetic testing on both levels of application, diagnostics, and prediction. This contribution aims to shed light on the changing concept of genetic testing as it is raised by novel cultural practices and perceptions mainly triggered by direct-to-consumer predictive testing, including the phenomenon of a new genetic exceptionalism "from below". We are seeking to determine what is at stake in this practice and what consequences arise from it for the medical and scientific community. What exactly happens as we move from diagnostic to prognostic medicine? Above all, this article pivots on the notion of captious certainties, a concept, which we will elaborate on as our argument progresses.

Year:  2013        PMID: 24203529      PMCID: PMC3890064          DOI: 10.1007/s12687-013-0172-y

Source DB:  PubMed          Journal:  J Community Genet        ISSN: 1868-310X


  21 in total

1.  Shattuck lecture--medical and societal consequences of the Human Genome Project.

Authors:  F S Collins
Journal:  N Engl J Med       Date:  1999-07-01       Impact factor: 91.245

2.  Gail model and breast cancer.

Authors:  M H Gail; M H Greene
Journal:  Lancet       Date:  2000-03-18       Impact factor: 79.321

3.  Prophylactic mastectomy for women with BRCA1 and BRCA2 mutations--facts and controversy.

Authors:  A Eisen; B L Weber
Journal:  N Engl J Med       Date:  2001-07-19       Impact factor: 91.245

4.  Users' motivations to purchase direct-to-consumer genome-wide testing: an exploratory study of personal stories.

Authors:  Yeyang Su; Heidi C Howard; Pascal Borry
Journal:  J Community Genet       Date:  2011-05-28

5.  Is there a doctor in the house? : The presence of physicians in the direct-to-consumer genetic testing context.

Authors:  Heidi Carmen Howard; Pascal Borry
Journal:  J Community Genet       Date:  2011-09-06

6.  What you don't know can hurt you: adverse psychologic effects in members of BRCA1-linked and BRCA2-linked families who decline genetic testing.

Authors:  C Lerman; C Hughes; S J Lemon; D Main; C Snyder; C Durham; S Narod; H T Lynch
Journal:  J Clin Oncol       Date:  1998-05       Impact factor: 44.544

7.  The lifetime risk of developing breast cancer.

Authors:  E J Feuer; L M Wun; C C Boring; W D Flanders; M J Timmel; T Tong
Journal:  J Natl Cancer Inst       Date:  1993-06-02       Impact factor: 13.506

8.  Experiences of early users of direct-to-consumer genomics in Switzerland: an exploratory study.

Authors:  E Vayena; E Gourna; J Streuli; E Hafen; B Prainsack
Journal:  Public Health Genomics       Date:  2012-11-15       Impact factor: 2.000

9.  The prognostic significance of Gail model risk factors for women with breast cancer.

Authors:  Paul Ian Tartter; Csaba Gajdos; Sharon Rosenbaum Smith; Alison Estabrook; Alfred W Rademaker
Journal:  Am J Surg       Date:  2002-07       Impact factor: 2.565

10.  Survey of European clinical geneticists on awareness, experiences and attitudes towards direct-to-consumer genetic testing.

Authors:  Heidi Carmen Howard; Pascal Borry
Journal:  Genome Med       Date:  2013-05-22       Impact factor: 11.117

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  3 in total

1.  Predictive genetic testing, risk communication, and risk perception: an international expert meeting in Berlin, Germany.

Authors:  Eva Fisher; Steffi Achilles; Holger Tönnies
Journal:  J Community Genet       Date:  2013-12-10

2.  Factors Associated with Acceptability, Consideration and Intention of Uptake of Direct-To-Consumer Genetic Testing: A Survey Study.

Authors:  Kelly F J Stewart; Daša Kokole; Anke Wesselius; Annemie M W J Schols; Maurice P Zeegers; Hein de Vries; Liesbeth A D M van Osch
Journal:  Public Health Genomics       Date:  2018-10-25       Impact factor: 2.000

Review 3.  Limiting medical certainties? Funding challenges for German and comparable public healthcare systems due to AI prediction and how to address them.

Authors:  Ulrich von Ulmenstein; Max Tretter; David B Ehrlich; Christina Lauppert von Peharnik
Journal:  Front Artif Intell       Date:  2022-08-01
  3 in total

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