Literature DB >> 24202567

Human exposure to aluminum.

S G Epstein1.   

Abstract

Aluminum is the third most abundant element in nature, accounting for nearly 8% of the Earth's crust. Because of its chemical activity, aluminum is not found naturally in its "free", or metallic, state. However, in its ionic or combined forms, aluminum is a truly ubiquitous element.Because of the widespread use of metallic aluminum in cooking and packaging applications, the Aluminum Association has funded critical reviews of the world's literature on the health effects of aluminum and aluminum compounds for the past 30 years.More recently, an extensive research and literature surveillance effort was developed to provide information on the neurological implications of aluminum, dietary intakes and body balance, and analytical capabilities. Based on these efforts the following conclusions can presently be drawn: (1) the cause (or causes) of Alzheimer's disease is not known; (2) the biological significance of aluminum found in the brain is not understood; (3) aluminum is poorly absorbed by the body; and (4) the normal ingestion of aluminum from food and water should have no adverse effects on human health.

Entities:  

Year:  1990        PMID: 24202567     DOI: 10.1007/BF01734050

Source DB:  PubMed          Journal:  Environ Geochem Health        ISSN: 0269-4042            Impact factor:   4.609


  18 in total

1.  Aluminum in the environment of man; a review of its hygienic status.

Authors:  I R CAMPBELL; J S CASS; J CHOLAK; R A KEHOE
Journal:  AMA Arch Ind Health       Date:  1957-05

2.  Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

Authors:  K S Kosik; C L Joachim; D J Selkoe
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

3.  Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Authors:  I Grundke-Iqbal; K Iqbal; M Quinlan; Y C Tung; M S Zaidi; H M Wisniewski
Journal:  J Biol Chem       Date:  1986-05-05       Impact factor: 5.157

Review 4.  Alzheimer's disease may begin in the nose and may be caused by aluminosilicates.

Authors:  E Roberts
Journal:  Neurobiol Aging       Date:  1986 Nov-Dec       Impact factor: 4.673

5.  Uptake of aluminium into central nervous system along nasal-olfactory pathways.

Authors:  D P Perl; P F Good
Journal:  Lancet       Date:  1987-05-02       Impact factor: 79.321

Review 6.  Alzheimer's disease.

Authors:  R Katzman
Journal:  N Engl J Med       Date:  1986-04-10       Impact factor: 91.245

Review 7.  The health effects of aluminum compounds in mammals.

Authors:  G L Krueger; T K Morris; R R Suskind; E M Widner
Journal:  Crit Rev Toxicol       Date:  1984       Impact factor: 5.635

8.  Revision of the Total Diet Study food list and diets.

Authors:  J A Pennington
Journal:  J Am Diet Assoc       Date:  1983-02

Review 9.  Aluminum and Alzheimer's disease.

Authors:  D R McLachlan
Journal:  Neurobiol Aging       Date:  1986 Nov-Dec       Impact factor: 4.673

Review 10.  Metabolism and possible health effects of aluminum.

Authors:  P O Ganrot
Journal:  Environ Health Perspect       Date:  1986-03       Impact factor: 9.031

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  1 in total

1.  Aluminium and heavy metals in potable waters of the north Ceredigion area, mid-Wales.

Authors:  R Fuge; W Perkins
Journal:  Environ Geochem Health       Date:  1991-06       Impact factor: 4.609

  1 in total

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