R Eckardt1, E Steinhagen-Thiessen, S Kämpfe, N Buchmann. 1. Forschungsgruppe Geriatrie der Charité Universitätsmedizin Berlin, Ev. Geriatriezentrum Berlin, Reinickendorfer Str. 61, 13347, Berlin, Deutschland, rahel.eckardt@charite.de.
Abstract
BACKGROUND: When used appropriately, drugs are an effective and efficient intervention in the care of patients. However, elderly, multimorbid patients are especially prone to adverse side effects caused by the simultaneous intake of many drugs--this effect is called polypharmacy. Furthermore, adverse medical effects occur more frequently with elderly people compared to younger patients. This is due to age-specific metabolic changes and issues with compliance and adherence. Therefore, the indication for medication should be taken carefully and individually especially for elderly patients, in order to develop a realistic risk-benefit ratio, taking into consideration questions like quality of life and life expectancy. MATERIALS AND METHODS: In this paper, the current medical care situation of elderly people is presented; problems are identified and analyzed. RESULTS: Supported by a selected literature search, recommendations for improving medication safety are summarized.
BACKGROUND: When used appropriately, drugs are an effective and efficient intervention in the care of patients. However, elderly, multimorbid patients are especially prone to adverse side effects caused by the simultaneous intake of many drugs--this effect is called polypharmacy. Furthermore, adverse medical effects occur more frequently with elderly people compared to younger patients. This is due to age-specific metabolic changes and issues with compliance and adherence. Therefore, the indication for medication should be taken carefully and individually especially for elderly patients, in order to develop a realistic risk-benefit ratio, taking into consideration questions like quality of life and life expectancy. MATERIALS AND METHODS: In this paper, the current medical care situation of elderly people is presented; problems are identified and analyzed. RESULTS: Supported by a selected literature search, recommendations for improving medication safety are summarized.
Authors: Michael A Steinman; C Seth Landefeld; Gary E Rosenthal; Daniel Berthenthal; Saunak Sen; Peter J Kaboli Journal: J Am Geriatr Soc Date: 2006-10 Impact factor: 5.562
Authors: Thomas Fiss; Adina Dreier; Claudia Meinke; Neeltje van den Berg; Christoph Alexander Ritter; Wolfgang Hoffmann Journal: Age Ageing Date: 2010-09-07 Impact factor: 10.668
Authors: Emma C Davies; Christopher F Green; Stephen Taylor; Paula R Williamson; David R Mottram; Munir Pirmohamed Journal: PLoS One Date: 2009-02-11 Impact factor: 3.240